PRECISION SHOCK-WAVE GENERATOR FOR MEDICAL TREATMENT AND RESEARCH

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1987
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
7214
Agency Tracking Number:
7214
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
14900 Sweitzer Lane, Laurel, MD, 20707
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
NICHOLAS PERRONE PHD
(301) 498-8200
Business Contact:
() -
Research Institution:
n/a
Abstract
THIS INVESTIGATION INTENDS TO EVALUATE THE CAPABILITY OF AN ESTABLISHED SECTOR SHOCK-TUBE METHOD FOR APPLICATION TO LITHOTRIPSY. IT COULD PROVIDE A QUANTITATIVELY DEFINED SHOCK WAVE IN TERMS OF WAVE PRESSURE, DURATION, ENERGY, AND SPATIAL EXTENT FOR IMPROVED PATIENT TREATMENT AND USE OF SHOCK WAVES IN BIOLOGICAL RESEARCH. THE ONLY AUTHORIZED SHOCK-WAVE LITHOTRIPSY TREATMENT SYSTEM (DORNIER)EMPLOYS AN ELLIPTICAL FOCUSING METHOD THAT, BECAUSE THE FOCUS IS A MATHEMATICAL SINGULARITY, IS, IN PRACTICE, INHERENTLY UNSTABLE AND NOT REPRODUCIBLE IN A PRESSURE AMPLITUDE AND POSITIONAL SENSE. ALL OTHER PROPOSED SYSTEMS HAVE SIMILAR LIMITATIONS. THE SECTOR SHOCK-WAVE METHOD, BECAUSE IT IS QUANTITATIVELY PREDICTABLE, CONTROLLABLE, AND REPRODUCIBLE, COULD LEAD TO LITHOTRIPSY TREATMENT THAT IS FASTER, SAFER, LESS DAMAGING, AND EASILY ADAPTABLE TO INDIVIDUAL PATIENT AND VARIOUS DSEASE REQUIREMENTS. THE RESEARCH EFFORT INCLUDES DESIGN AND FABRICATION OF A CONICAL SECTOR SHOCK TUBE THAT WILL BE USED TO SHOCK IMPACT-SIMULATED AND ACTUAL STONES WHILE TRANSIENT PRESSURE MEASUREMENTS ARE MADE. HYDRODYNAMICS CODE CALCULATIONS WILL ASSIST EXPERIMENTAL DESIGN AND CORRELATION OF RESULTS. PHASE II STUDIES WITH ANIMALS AND HUMANS WILL BE BASED ON THESE RESULTS. COMMERCIALLY, THIS COULD PROVIDE AN ADVANCEDTHIRD-GENERATION LITHOTRIPSY SYSTEM, A UNIQUE QUANTITATIVE BIOLOGICAL RESEARCH TOOL, AND A RETROFIT SHOCK-WAVE SOURCE TO UPGRADE EXISTING LITHOTRIPSY SYSTEMS.

* information listed above is at the time of submission.

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