N/A

Award Information
Agency:
National Science Foundation
Branch
n/a
Amount:
$100,000.00
Award Year:
2001
Program:
SBIR
Phase:
Phase I
Contract:
0109691
Award Id:
53191
Agency Tracking Number:
0109691
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
45 Manning Road, Billerica, MA, 01821
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Douglas Worsnop
(978) 663-9500
worsnop@aerodyne.com
Business Contact:
Charles Kolb
President
(978) 663-9500
kolb@aerodyne.com
Research Institution:
n/a
Abstract
This Small Business Innovation Research Phase I (SBIR) project will develop a new class of real time aerosol mass spectrometers (AMSs) for analysis of respirable powder and liquid aerosol in pulmonary drug delivery systems. Three parameters control the effective delivery of drugs to the lungs: (1) the number density of entrained aerosol particles per unit volume of respirable fluid; (2) the particle size distribution; (3) the concentrations of active ingredients as a function of particle size. Aerosol Mass Spectrometers, with proper calibration, can measure all three parameters simultaneously. Aerodyne Research, Inc. (ARI), in collaboration with several university research groups, has developed, demonstrated, and commercialized an innovative and quantitative AMS system. With suitable modification and calibration, this system could greatly reduce the time and effort required to characterize pulmonary drug delivery systems, both for research and for production quality assurance. This Phase I project will design and test a real-time AMS system to characterize novel pulmonary drug delivery systems. The principal commercial application of this project will be in the pulmonary drug delivery analyzer market. Potential customers are likely to include drug delivery companies, pharmaceutical companies, academic research organizations and regulatory agencies.

* information listed above is at the time of submission.

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