SBIR Phase I: Biodegradable Elastomers of Intravascular Drug Delivery

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: 0839732
Agency Tracking Number: 0839732
Amount: $100,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2009
Solicitation Year: N/A
Solicitation Topic Code: BC
Solicitation Number: NSF 08-548
Small Business Information
1801 Maple Ave Suite 6322, Evanston, IL, 60201
DUNS: 807388595
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: Y
Principal Investigator
 Antonio Webb
 (773) 266-8819
Business Contact
 Antonio Webb
Title: DPhil
Phone: (773) 266-8819
Research Institution
This Small Business Innovation Research (SBIR) Phase I project will develop a cell and blood compatible, non-clotting drug-eluting prosthetic artery that can release, in a controlled manner, drugs or other small compounds that can inhibit scarring and clotting. Potential drug candidates will be loaded using various concentrations and conditions, in order to determine the release rate and dosing that should be used to move the technology forward towards human application. It is expected that grafts will show controlled release and an effect on vascular cells tested in the lab. The broader impacts of this research include the development of engineering principles that will facilitate the fabrication of drug-eluting grafts that could potentially be useful in: a) procedures to correct blood flow occlusion due to peripheral artery disease, b) vascular access grafts for hemodialysis patients, and c) procedures where traditional prosthetic grafts cannot be used such as coronary artery bypass. This innovative technology and product has the potential to reduce the incidence of limb amputation and have a significant impact on the care of patients with vascular disease.

* Information listed above is at the time of submission. *

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government