ECIS Wound Healing High-Throughput Assay

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$70,000.00
Award Year:
2005
Program:
SBIR
Phase:
Phase I
Contract:
W911NF-05-C-0017
Agency Tracking Number:
A043-071-1724
Solicitation Year:
2004
Solicitation Topic Code:
A04-071
Solicitation Number:
2004.3
Small Business Information
AGAVE BIOSYSTEMS, INC.
P.O. Box 80010, Austin, TX, 78708
Hubzone Owned:
N
Socially and Economically Disadvantaged:
Y
Woman Owned:
N
Duns:
022552900
Principal Investigator:
Theresa Curtis
Staff Scientist
(607) 272-0002
tcurtis@agavebio.com
Business Contact:
Noe Salazar
President
(512) 671-1369
nsalazar@agavebio.com
Research Institution:
n/a
Abstract
Healing of a wound is a complex and protracted process of tissue repair and remodeling in response to injury. Understanding how the body repairs damaged tissue and what genes and biochemical factors influence the wound healing process will have tremendous impact on the treatment of chronic wounds and the regeneration of tissue and organ function after injury. To facilitate the discovery of genes and compounds that are involved in wound healing, Agave BioSystems will develop an in vitro cell based system that will allow high-throughput analysis of genes and chemical compounds that may have a therapeutic affect in wound healing. This high-throughput, in vitro, wound healing assay will utilize small interfering RNA to specifically interfere with the function of genes of interest and Electric Cell-Substrate Impedance Sensing (ECIS) to non-invasively monitor the kinetics of fibroblast and epithelial wound healing.

* information listed above is at the time of submission.

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