Water Toxicity Detection using Genetically Engineered Yeast
Small Business Information
AGAVE BIOSYSTEMS, INC.
P.O. Box 100, Ithaca, NY, 14850
AbstractThe rapid evaluation of drinking water toxicity in the field is a necessity for the safety of our soldiers. To achieve field portability and sensitive screening for identification of toxic industrial chemicals (TICs) a handheld device that is biologically-based and easy to use with components that remain viable for 6 months would be ideal. In this Phase I, Agave BioSystems proposes to develop an accurate and efficient cell-based biosensor using engineered yeast to rapidly evaluate toxicity in drinking water. This methodology will use Saccharomyces cerevisiae yeast measuring two different outcomes to ensure TIC detection accuracy. This novel yeast strain will be lyophilized for long term storage and is expected to be responsive to a variety of TICs.
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