Water Toxicity Detection using Genetically Engineered Yeast

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$70,000.00
Award Year:
2009
Program:
SBIR
Phase:
Phase I
Contract:
W81XWH-09-C-0073
Award Id:
92020
Agency Tracking Number:
A083-174-0418
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
P.O. Box 100, Ithaca, NY, 14850
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
022552900
Principal Investigator:
KathieBerghorn
Staff Scientist
(607) 272-0002
kberghorn@agavebio.com
Business Contact:
NoeSalazar
President
(512) 656-6200
nsalazar@agavebio.com
Research Institute:
n/a
Abstract
The rapid evaluation of drinking water toxicity in the field is a necessity for the safety of our soldiers. To achieve field portability and sensitive screening for identification of toxic industrial chemicals (TICs) a handheld device that is biologically-based and easy to use with components that remain viable for 6 months would be ideal. In this Phase I, Agave BioSystems proposes to develop an accurate and efficient cell-based biosensor using engineered yeast to rapidly evaluate toxicity in drinking water. This methodology will use Saccharomyces cerevisiae yeast measuring two different outcomes to ensure TIC detection accuracy. This novel yeast strain will be lyophilized for long term storage and is expected to be responsive to a variety of TICs.

* information listed above is at the time of submission.

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