EXTENSIBLE HERMETIC NEURAL INTERFACE MICROSYSTEMS

The goal of this program is to develop a one-size-fits-many solution for implantable, wireless recording and stimulation with a variety of implantable electrode array types for neuroscience and neuroprosthesis research.The implants in this program will be enclosed in hermetic, ceramic packages with feed-throughs to accommodate up to 32 electrodes for each implant.The implants will be powered via inductive telemetry from an external transceiver placed directly over the implant, and data exchange will be accomplished through a combination of local inductive and transcutaneous infrared telemetry.The amplifier and telemetry will be programmable for sampling rates between 1 to 30 ksps at up to 16 bits resolution for supporting both low-frequency and higher frequency extracellular recordings.The local nature of these telemetry modes will allow multiple implants to be operated in proximity in the same subject.In parallel with this development, we will also complete a wearable data acquisition platform with programmable capabilities for real-time closed loop recording and stimulation.At the end of this program, the implants and external electronics will be sufficiently tested and qualified such that they can be approved for use with human studies for specific electrodes with minimal follow-on animal studies.