Innovative and Low Cost Process to Produce Isoamyl Acetate using Metabolically Engineered E.Coli

Award Information
Agency:
Department of Agriculture
Branch
n/a
Amount:
$79,995.00
Award Year:
2004
Program:
SBIR
Phase:
Phase I
Contract:
2004-33610-14308
Award Id:
67168
Agency Tracking Number:
2004-00503
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
1500 Hayes Drive, Manhattan, KS, 66502
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
PraveenVadlani
(785) 537-0088
vadlani@kansas.net
Business Contact:
GaryRabold
Interim President
(785) 532-3900
grabold@ksu.edu
Research Institute:
n/a
Abstract
Natural flavor compounds find wide applications in the food, feed, cosmetic, chemical and pharmaceutical industry, and isoamyl acetate is an important flavor ester. In this research program, a low-cost process is proposed to convert glucose from renewable sources to isoamyl acetate using a high-yielding metabolically engineered E coli. Isoamyl acetate produced via chemical synthesis results in an undesirable racemic mixture. The fermentation route followed in this program will result in high yields of "natural" isoamyl acetate with additional usage in food industry along with other uses The proposed research will lay the foundation for isoamyl acetate biosynthesis at high yield from renewable sugars. Successful outcome of the project will provide a platform for the low-cost production of additional high-valued natural esters.

* information listed above is at the time of submission.

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