Innovative and Low Cost Process to Produce Isoamyl Acetate using Metabolically Engineered E.Coli

Award Information
Agency: Department of Agriculture
Branch: N/A
Contract: 2004-33610-14308
Agency Tracking Number: 2004-00503
Amount: $79,995.00
Phase: Phase I
Program: SBIR
Awards Year: 2004
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
AgRenew, Inc.
1500 Hayes Drive, Manhattan, KS, 66502
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Praveen Vadlani
 (785) 537-0088
Business Contact
 Gary Rabold
Title: Interim President
Phone: (785) 532-3900
Research Institution
Natural flavor compounds find wide applications in the food, feed, cosmetic, chemical and pharmaceutical industry, and isoamyl acetate is an important flavor ester. In this research program, a low-cost process is proposed to convert glucose from renewable sources to isoamyl acetate using a high-yielding metabolically engineered E coli. Isoamyl acetate produced via chemical synthesis results in an undesirable racemic mixture. The fermentation route followed in this program will result in high yields of "natural" isoamyl acetate with additional usage in food industry along with other uses The proposed research will lay the foundation for isoamyl acetate biosynthesis at high yield from renewable sugars. Successful outcome of the project will provide a platform for the low-cost production of additional high-valued natural esters.

* information listed above is at the time of submission.

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