A Chip-Scale Sensor for High-Throughput Detection of Multiple Waterborne Pathogens

Award Information
Agency: Department of Defense
Branch: Defense Advanced Research Projects Agency
Contract: N10PC20077
Agency Tracking Number: 09SB3-0175
Amount: $98,998.00
Phase: Phase I
Program: SBIR
Awards Year: 2010
Solicitation Year: 2009
Solicitation Topic Code: SB093-010
Solicitation Number: 2009.3
Small Business Information
362 Industrial Park Road, Suite #8, Middletown, CT, 06457
DUNS: 076890222
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Frank Inscore
 Director of Raman Applications
 (860) 635-9800
Business Contact
 Stuart Farquharson
Title: President
Phone: (860) 635-9800
Email: stu@rta.biz
Research Institution
The overall goal of this proposed program (through Phase III) is to develop a chip-scale assay that can detect, identify, and quantify the presence of Category A (or B) bioagents in water at the required sensitivity (e.g. 400 B. anthracis spores or 15 µg of ricin per liter water) within 10 minutes. During the Phase I program feasibility will be demonstrated by 1) functionalizing silver particles to specifically bind B. anthracis-Sterne and 2) detecting the capture event by surface-enhanced Raman spectroscopy (SERS). During the Phase II program, a prototype will be designed built and tested, with superior weight, size and power in mind for integration into military equipment during the transition phase. The initial part of the Phase III transition phase will involve validation tests of Category A pathogens at the US Army’s Edgwood Chem Bio Center to bring the prototype to a technology transition level of 6.

* Information listed above is at the time of submission. *

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