OpenClinica: Open Source Platform for Clinical Research

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$343,444.00
Award Year:
2007
Program:
SBIR
Phase:
Phase II
Contract:
2R44RR019837-03A1
Agency Tracking Number:
RR019837
Solicitation Year:
2007
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
AKAZA RESEARCH
AKAZA RESEARCH, 1 KENDALL SQ, BLDG 400, 4TH FL, CAMBRIDGE, MA, 02139
Hubzone Owned:
Y
Socially and Economically Disadvantaged:
Y
Woman Owned:
Y
Duns:
364179312
Principal Investigator:
CAL COLLINS
(617) 621-8585
CCOLLINS@akazaresearch.com
Business Contact:
CAL COLLINS
(617) 621-8585
ccollins@akazaresearch.com
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant): We believe a key barrier to transforming clinical research is the lack of open, integrated, transparent technology solutions that address bottlenecks in information integration and business process management. Our viewpoint is supported by a recent Forrester Research study that identifies proprietary software as "one of the biggest barriers" to interoperability in the health IT environment, and suggests wider use of open source software to address integration challenges. I This project will build on Akaka's OpenClinica platform, the leading open source clinical research solution, to develop a broad-based open source software infrastructure that enables interoperability in heterogeneous clinical and translational research, and to develop targeted commercially-supported open source solutions from this infrastructure. It will: Integrate research data across distributed heterogeneous data sources, even data from legacy sources with poor interfaces and data documentation. Automate exchange of information with other systems in the healthcare and clinical research enterprises via semantically harmonized domain models and standardized messaging interfaces. Facilitate transition of paper-based processes to electronic systems for electronic data capture of case report forms (CRFs) and patient diaries (ePRO, or electronic Patient Reported Outcomes). Improve research management and monitoring in a Good Clinical Practice-compliant environment. The resulting solution will advance the capabilities of the clinical and translational research enterprise and empower collaborative research at Academic Health Centers (AHCs), government agencies, Contract Research Organizations (CROs), and the biopharmaceutical industry. It will increase the throughput and efficiency of clinical research, operate reliably in heterogeneous environments, and enable new types of research by bringing together disparate research tools and data.

* information listed above is at the time of submission.

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