Malaria Diagnostic Methods to Replace Microscopy in Clinical Trials

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$69,981.00
Award Year:
2008
Program:
SBIR
Phase:
Phase I
Contract:
W81XWH-09-C-0012
Agency Tracking Number:
A082-118-1972
Solicitation Year:
2008
Solicitation Topic Code:
A08-118
Solicitation Number:
2008.2
Small Business Information
AKRON RUBBER DEVELOPMENT LABORATORY, INC
2887 Gilchrist Rd, Akron, OH, 44305
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
077781706
Principal Investigator:
Ana Barbur
Chemical Services Manager
(330) 794-6600
anab@ardl.com
Business Contact:
Jerry Leyden
President
(330) 794-6600
jerry@ardl.com
Research Institution:
n/a
Abstract
Developing a robust and accurate test for the detection of malaria continues to be an elusive challenge.1,2 The objective of this proposal is to develop an innovative approach to the diagnosis of malaria that is very specific and sensitive for detecting the presence of malaria parasites in red blood cells (RBC). This approach could potentially be more effective than the current microscopic and rapid detection tests that seem to have issues with both false positives and negatives. A novel approach is necessary to explore other untapped avenues and identify a new methodology to achieve this objective. As ARDL, Inc.’s newly established division, ARDL Pharmaceutical Services Lab is uniquely positioned to address this objective. Phase I would consist of characterization of extracts of standard RBC that contain the malaria parasite, Plasmodium. Phase II of the proposal would then be focused on translating the results from the Phase I proof of principle demonstration into a robust method with the ultimate goal to develop a simple, low cost, modular type test that could be used for diagnostic purposes in remote areas of the world.

* information listed above is at the time of submission.

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