SENSITIVE PROBE FOR INTRAOPERATIVE BONE SCANNING

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 2959
Amount: $260,000.00
Phase: Phase II
Program: SBIR
Awards Year: 1986
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
44 Hunt Street, Watertown, MA, 02172
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Gerald Entine
 Principal Investigator
 (617) 926-1167
Business Contact
Phone: () -
Research Institution
N/A
Abstract
ONE OF THE MOST CRITICAL CONSIDERATIONS IN THE SUCCESSFUL TREATMENT OF BONE TUMORS AND INFECTIONS IS THEIR DETECTION AND LOCALIZATION DURING SURGERY. ALTHOUGH NUCLEAR MEDICINE SCANNING TECHNIQUES ARE A WIDELY ACCEPTED AND EFFECTIVE APPROACH FOR IMAGING, THEY ARE VERY DIFFICULT TO USE IN THE TIGHT CONFINES OF THE OPERATING ROOM. THIS LIMITATION IS PARTICULARLY IMPORTANT IN THE REMOVAL OF A WIDE VARIETY OF BONE LESIONS IN WHICH THE INFECTED TISSUE SHOWS LITTLE OR NO ANATOMICAL ABNORMALITY. IN VIRTUALLY ALL OF THESE CASES, THE DIFFICULTY IN DEFINING THE BOUNDARIES OF THE LESIONS RESULTS IN THE REMOVAL OF EITHER TOO MUCH OR TOO LITTLE TISSUE AND CAUSES THE ATTENDANT CLINICAL CONSEQUENCES.RECENT CLINICAL EXPERIMENTS HAVE INDICATED THAT A SENSITIVE, HAND-HELD, NUCLEAR PROBE COULD BE OF GREAT ASSISTANCE IN LOCALIZING BONE LESIONS DURING SURGERY. RMD, INC., IN COLLABORATION WITH QUEEN'S MEDICAL CENTER AND THE UNIVERSITY OF ROCHESTER MEDICAL CENTER, PROPOSES TO DO THE RESEARCH NECESSARY TO DEVELOP AN EXTREMELY SENSITIVE, MINIATURIZED INSTRUMENT FOR INTRAOPERATIVE BONE SCANNING. THIS NEW HAND-HELD DEVICE WILL ALLOW SURGEONS TO ACCURATELY LOCATE TUMOROUS OR DISEASED TISSUE DURING BIOPSY OR RESECTION AND PROVIDE A VERY VALUABLE TECHNIQUE FOR THE SUCCESSFUL TREATMENT OF

* Information listed above is at the time of submission. *

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