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PERIDONTAL DISEASE IS ONE OF THE MOST WIDESPREAD MEDICAL PROBLEMS FACING THE NATION TODAY.

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 3140
Amount: $50,000.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 1985
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
44 Hunt Street, Watertown, MA, 02172
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 GERALD ENTINE
 PRINCIPAL INVESTIGATOR
 (617) 926-1167
Business Contact
Phone: () -
Research Institution
N/A
Abstract
PERIDONTAL DISEASE IS ONE OF THE MOST WIDESPREAD MEDICAL PROBLEMS FACING THE NATION TODAY. CRUCIAL TO THE SUCCESSFUL TREATMENT OF THIS DISEASE IS EARLY DETECTION AS WELL AS CAREFUL MONITORING OF THE PROGRESS OF THE PERIODONTAL THERAPY. THERE ARE, HOWEVER, FEW EFFECTIVE APPROACHES TO THIS PROBLEM AND, FOR THE PRESENT, PERIODONTISTS MUST STILL RELY VERY HEAVILY ON DENTAL X-RAYS. UNFORTUNATELY, WHILE X-RAYS PROVIDE AN EXCELLENT WAY TO DIAGNOSE DENTAL CARIES, THE QUALITY OF RADIOGRAPHS IS NOT CONSISTENTLY HIGH ENOUGH TO OBTAIN RELIABLE DATA FOR STUDYING THE AVEOLAR BONE LOSS WHICH ACCOMPANIES PERIODONTAL DISEASE. THE CONTROL OF EXPOSURE IS MUCH MORE CRITICAL IN X-RAYS USED FOR PERIODONTAL EXAMINATION THAN FOR THOSE USED IN BASIC DENTISTRY BECAUSE THE DETECTION OF THE BOUNDARY OF THE ALVEOLAR BONE REQUIRES OPTIMUM CONTRAST. RADIOGRAPHIC MONITORING OF CHRONIC DESTRUCTIVE PERIODONTAL DISEASE IS HIGHLY DEPENDENT ON THE ABILITY OF THE CLINICIAN TO COMPARE SEQUENTIAL RADIOGRAPHS. ALTHOUGH SEVERAL FACTORS CAN CONTRIBUTE TO THE VARIABILITY OF THE QUALITY OF RADIOGRAPHS, THE MOST IMPORTANT CAUSE IS POOR CONTROL OF FILM EXPOSURE. THE OVERALL GOAL OF THIS PROGRAM IS TO CONDUCT THE DETECTOR AND INSTRUMENTATION RESEARCH NEEDED TO MAKE AN AUTOMATIC X-RAY EXPOSURE CONTROLLER FOR USE IN THE DIAGNOSIS OF PERIODONTAL DISEASE. DURING PHASE I, WE WILL FOCUS ON THE DEVELOPMENT OF THE X-RAY SENSOR AND DEMONSTRATE THAT IT IS FEASIBLE TO USE SUCH A DEVICE FOR THIS PURPOSE. IN PHASE II OF THE PROGRAM, THE DETECTOR RESEARCH WILL BE COMPLETED AND A FULLY OPERATIONAL, EXPERIMENTAL PROTOTYPE SYSTEM WILL BE CONSTRUCTED AND TESTED WITH CLINICAL PHANTOMS IN COLLABORATION WITH THE HARVARD SCHOOL

* Information listed above is at the time of submission. *

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