RENAL BLOOD FLOW MONITOR FOR ICU PATIENTS

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$500,000.00
Award Year:
1989
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Award Id:
7982
Agency Tracking Number:
7982
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
44 Hunt St, Watertown, MA, 02172
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
ACUTE RENAL FAILURE IS A MAJOR CONTRIBUTING CAUSE OF DEATH IN PATIENTS IN THE INTENSIVE CARE UNIT PARTLY DUE TO THE LACK OF A SIMPLE, RAPID METHOD OF ASSESSING KIDNEY FUNCTION. IT WOULD THEREFORE BE EXTREMELY USEFUL IF A DIRECT MEASUREMENT OF RENAL FUNCTION COULD BE PERFORMED AT REGULAR INTERVALS SO THAT THE NEED FOR ANY MEDICAL OR SURGICAL INTERVENTION COULD BE IDENTIFIED BEFORE ANY SIGNIFICANT DAMAGE OCCURRED TO THE KIDNEYS OR OTHER ORGANS DUE TO RENAL FAILURE. WE PROPOSE TO DEVELOP A PRACTICAL, COST EFFECTIVE INSTRUMENTAND PROTOCOL TO PROVIDE THE RENAL BLOOD FLOW (RBF) DATA NECESSARY TO MONITOR RENAL CONDITION AND PREDICT POSSIBLE FAILURE IN ICU PATIENTS. THE PROPOSED SOLID STATE, NUCLEAR DETECTION SYSTEM AND ACCOMPANYING NUCLEAR MEDICAL PROTOCOLS SHOULD FULFILL THIS NEED. BY THE END OF THE PHASE I PROGRAM, THE TECHNOLOGY WILL HAVE BEEN SUFFICIENTLY DEVELOPED AND TESTED TO CLEARLY DEMONSTRATE THE FEASIBILITY OF MEASURING RENAL BLOOD FLOW IN THE ICU. THE DEVELOPMENT OF THIS NEW MONITORING CAPABILITY WILL LEAD TO AN IMPORTANT ADVANCEMENT IN THE FIELD OF RENAL FUNCTION ANALYSIS AS WELL AS THE CREATION OF A POTENTIALLY SUCCESSFUL TECHNICAL PRODUCT.

* information listed above is at the time of submission.

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