MICRODOSIMETRIC SOLID STATE TISSUE EQUIVALENT DETECTOR

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1991
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
16388
Agency Tracking Number:
16388
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
44 Hunt Street, Watertown, MA, 02172
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Entine, Gerald
Principal Investigator
(617) 926-1167
Business Contact:
1 R43 CA53944-01
() -
Research Institution:
n/a
Abstract
THE CONCERN OVER THE POTENTIAL HAZARDS OF LOW LEVEL RADIATION EXPOSURE IS INCREASING AS THE UNDERSTANDING OF ITS BIOLOGICAL EFFECTS INCREASES, PARTICULARLY IN ASSESSING THE RISK TO PERSONNEL WHO RECEIVE OCCUPATIONAL EXPOSURE TO RADIATION. CURRENT RADIATION RISK ASSESSMENT METHODS USE GLOBAL, NONSTOCHASTIC QUANTITIES, I. E., LARGE MASS OR VOLUME AVERAGED QUANTITIES, TO CHARACTERIZE RADIATION AND ITS BIOLOGICAL EFFECTS. THIS APPROACH CANNOT BE USED TO MEASURE AND UNDERSTAND THE EFFECTS AT THE CELLULAR LEVEL. THE PROBLEM WITH THIS IS THAT MOST MEDICAL PROBLEMS CAUSED BY RADIATION EXPOSURE ARE DUE TO DAMAGE TO INDIVIDUAL CELLS. THUS, TO UNDERSTAND THE MECHANISMS CAUSING THE DAMAGE, IT IS NECESSARY TO DEVELOP NEW SENSORS TO MEASURE INTERACTIONS AT THAT MICROSCOPIC CELLULAR LEVEL. EXISTING DETECTOR TECHNOLOGY IS NOT ADEQUATE FOR MAKING MICRODOSIMETRIC MEASUREMENTS. NEW TYPES OF DETECTORS ARE NEEDED TO FILL THE NEED BOTH FOR RESEARCH AND FOR PERSONNEL MONITORING. THIS RESEARCH EFFORT WILL INVESTIGATE THE FABRICATION OF TISSUE EQUIVALENT, SOLID STATE DETECTORS FOR USE IN MICRODOSIMETRY.

* information listed above is at the time of submission.

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