Novel Wear Resistant and Thermally Insulative Materials

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$730,000.00
Award Year:
2001
Program:
SBIR
Phase:
Phase II
Contract:
DAAD13-00-C-5003
Award Id:
48442
Agency Tracking Number:
A992-1414
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
44 Hunt Street, Watertown, MA, 02472
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
073804411
Principal Investigator:
Arieh Karger
Group Leader
(617) 926-1167
fries@mrcsb.com
Business Contact:
Gerald Entine
Group Leader
() -
fries@mrcsb.com
Research Institute:
n/a
Abstract
The Phase I effort successfully integrated micro-APD arrays into a detection system that can accommodate many microscale analysis platforms, including genomic-based systems on glass, silicon, plastic and PDMS (poly-dimethylsiloxane). We demonstrated thefeasibility of our detection platform by developing a highly sensitive, low-cost prototype system, which consisted of an LED excitation source, an optical fiber, two plastic colored filters, the PDMS-based microfluidics, and the micro-APD detector array.This system achieved a sensitivity that measured concentrations of dilute fluorecein solutions down to 1 micro-M, and easily detected 3 micro-m diameter fluorescent latex spheres, which mimic tagged bacteria.We will research methods for identifying biological agents using a microfabricated sensing platform, and we will develop a low-cost, low-power, portable prototype that is capable of detecting and identifying bacteria in volumes of 100 micro-L, or less.With the addition of a sample collection and preparation module, the target sensitivity of the proposed system will provide a minimum detection sensitivity of 20 colony forming units (cfu)/liter of air for bacteria. The targeted identification responsetime is less than 5 minutes. The proposed microscale analysis system is based on the integration of a highly sensitive, photon-counting detection platform utilizing micro-APD arrays.

* information listed above is at the time of submission.

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