HIGH RESOLUTION/ SENSITIVITY PET IMAGING OF SMALL ANIMAL

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 1R43CA091397-01
Amount: $276,045.00
Phase: Phase I
Program: SBIR
Awards Year: 2001
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
RADIATION MONITORING DEVICES INC
44 HUNT ST, WATERTOWN, MA, 02172
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 MICHAEL SQUILLANTE
 () -
Business Contact
Phone: (617) 926-1167
Email: GENTINE@RMDINC.COM
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) is an in vivo analog of autoradiography and has the potential to become a powerful new tool in imaging biological processes in small laboratory animals. With the ever increasing number of human disease models, particularly in the smaller animals such as mice and rats, high resolution radionuclide imaging (such as PET) of small animals can contribute unique information. The critical advantage of PET is that it allows functional information to be obtained non-invasively, so each animal can be studied repeatedly. Clinical PET scanners used for human imaging are bulky, expensive and do not have adequate spatial resolution for small animal studies. Hence, dedicated, low cost instruments are required for conducting small animal studies with higher spatial resolution than what is currently achieved with clinical PET scanners. The goal of the proposed effort is to investigate a novel approach for designing a high resolution PET system. PROPOSED COMMERCIAL APPLICATION: Radionuclide imaging (PET, SPECT, gamma-camera, surgical probes), high energy physics, nuclear and health physics, nuclear treaty verification, nuclear safeguards.

* information listed above is at the time of submission.

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