High Resolution, High Sensitivity PET Imaging of Small *

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 9R44EB001924-03
Agency Tracking Number: CA091397
Amount: $923,197.00
Phase: Phase II
Program: SBIR
Awards Year: 2003
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
RADIATION MONITORING DEVICES, INC.
RADIATION MONITORING DEVICES INC, 44 HUNT ST, WATERTOWN, MA, 02472
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 MICHAEL SQUILLANTE
 (617) 668-6808
 MSQUILLANTE@RMDINC.COM
Business Contact
 GERALD ENTINE
Phone: (617) 926-1167
Email: GENTINE@RMDINC.COM
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) is an in vivo analog of autoradiography and has the potential to become a powerful new tool in imaging biological processes in small laboratory animals. With the ever increasing number of human disease models (including cancer) in the small laboratory animals such as mice and rats, high resolution PET imaging of small animals can contribute unique information. The critical advantage of PET is that it allows functional information to be obtained non-invasively, so each animal can be studied repeatedly. Thus, it is clear that PET imaging of small animals is highly desirable. Clinical PET scanners used for human imaging are bulky, expensive and do not have adequate spatial resolution for small animal studies. Hence, dedicated, low cost instruments are required for conducting small animal studies with higher spatial resolution than what is currently achieved with clinical PET scanners. The goal of the proposed Phase II project is to investigate a novel approach to produce a prototype small animal PET imager with very high spatial resolution and high sensitivity. Commercial Potential: Nuclear medicine including positron emission tomography and single photon emission computed tomography, radiology, non-destructive testing, materials research, X-ray diffraction, nuclear and high energy physics research, astronomy, and geological exploration.

* information listed above is at the time of submission.

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