HIGH RESOLUTION NUCLEAR CARDIAC IMAGING

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R43HL083494-01
Agency Tracking Number: HL083494
Amount: $100,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2006
Solicitation Year: 2006
Solicitation Topic Code: N/A
Solicitation Number: PHS2006-2
Small Business Information
RADIATION MONITORING DEVICES, INC.
44 Hunt Street, Watertown, MA, 02472
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 GERALD ENTINE
 (617) 926-1167
 GENTINE@RMDINC.COM
Business Contact
 GERALD ENTINE
Phone: (617) 668-6801
Email: GENTINE@RMDINC.COM
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): Nuclear medicine imaging modalities such as single photon emission computed tomography (SPECT) and positron emission tomography (PET) are powerful, non-invasive medical imaging techniques that provide an image of the three dimensional distribution of a radionuclide in any slice through an organ under study in the body [Phelps]. These images allow investigation of metabolism in the region being studied and are a useful tool for understanding the functioning of the organs as well as diagnosing symptoms of diseases. Nuclear medicine is a very important modality in cardiac imaging, providing both diagnosis as well as prognosis. SPECT is commonly used in localizing coronary artery disease and as many as 90% of myocardial perfusion studies are now performed using SPECT. The role of PET in cardiac imaging is gradually expanding, particularly in the areas of detecting coronary artery disease (where it shows -10 to 15% higher accuracy then SPECT) and assessing myocardial viability [Gunn Bronson]. Recent developments in combining nuclear medicine with X-ray CT imaging provide better attenuation correction in cardiac imaging studies. It is clear that nuclear medicine technologies are playing a prominent and an increasingly important role in cardiac care and clinical diagnosis. However, there is urgent need for improvement in the performance of these imaging modalities in order to exploit their full potential. The goal of the proposed effort is to investigate a new high resolution detector for nuclear medicine.

* information listed above is at the time of submission.

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