Solid-State Photosensor for PET

Award Information
Agency:
Department of Health and Human Services
Amount:
$100,000.00
Program:
SBIR
Contract:
1R43NS060197-01
Solitcitation Year:
2007
Solicitation Number:
N/A
Branch:
N/A
Award Year:
2007
Phase:
Phase I
Agency Tracking Number:
NS060197
Solicitation Topic Code:
N/A
Small Business Information
RADIATION MONITORING DEVICES, INC.
44 Hunt Street, Watertown, MA, 02472
Hubzone Owned:
Y
Woman Owned:
Y
Socially and Economically Disadvantaged:
Y
Duns:
073804411
Principal Investigator
 GERALD ENTINE
 (617) 926-1167
 GENTINE@RMDINC.COM
Business Contact
 JOANNE GLADSTONE
Phone: (617) 668-6801
Email: JGLADSTONE@RMDINC.COM
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) is a functional imaging technique with potential to quantify the rates of biological processes in vivo. The availability of short lived positron-emitting isotopes of carbon, nitrogen, oxygen and especially fluorine allows virtually any compound of biological interest to be labeled in trace amounts and introduced into the body for imaging with PET. The distribution of the tracer is imaged dynamically, allowing the rates of biological processes to be calculated using appropriate mathematical models. PET imaging can provide diagnosis for symptoms of diseases such as Alzheimer's disease, head trauma, and stroke. PET technology is also playing a prominent and an increasingly visible role in modern cancer research, clinical diagnosis and oncology. While PET is a powerful imaging tool, the performance of current clinical PET systems is limited by the available detector technology and there is an urgent need for improvement in PET instrumentation in order to exploit the full potential of this promising technique. The goal of the proposed effort is to design, build and implement new, solid-state photodetectors for reading out scintillation crystals in PET imaging.

* information listed above is at the time of submission.

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