Novel Photon Counting Detector for Small Animal SPECT/MRI

Award Information
Agency:
Department of Energy
Branch
n/a
Amount:
$99,999.00
Award Year:
2009
Program:
SBIR
Phase:
Phase I
Contract:
DE-FG02-09ER85384
Award Id:
94623
Agency Tracking Number:
91185
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
44 Hunt Street, Watertown, MA, 02472
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
073804411
Principal Investigator:
Gerald Entine
Dr.
(617) 668-6800
GEntine@rmdinc.com
Business Contact:
Gerald Entine
Dr.
(617) 668-6800
GEntine@rmdinc.com
Research Institute:
n/a
Abstract
Single photon emission computed tomography (SPECT) maintains an important role in the study of disease models in small animals. Although rich in physiological information content, the interpretation of SPECT data is challenging because SPECT images lack anatomical information. While high-resolution SPECT systems suitable for small animal imaging have been developed, none of these is compatible with small animal MRI systems to form a combined SPECT/MRI modality, which would provide the anatomical information. This project will develop a cost-effective, high-resolution, digital, photon-counting detector for small animal SPECT that could be integrated into existing small animal MRI systems. The module will consist of a new and specially-designed CMOS Digital Pixel Sensor (DPS) readout coupled to a high sensitivity radiation sensor. Phase I will demonstrate the feasibility of developing a high resolution photon-counting ¿-ray detector for simultaneous SPECT/MRI combined imaging, based on a radiation sensor coupled to this newly-designed DPS sensor. Commercial Applications and other Benefits as described by the awardee The new detector should have widespread use in small animal and human multi-modality imaging systems. Additionally, the readout sensor should have applications in photon-counting X-ray imaging, bioluminescence imaging, nondestructive testing, and homeland security

* information listed above is at the time of submission.

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