ALKERMES, INC.

Company Information

Company Name
ALKERMES, INC.
Address
64 SIDNEY ST
CAMBRIDGE, MA, 02139
Phone
1 617-494-0171
URL
n/a
DUNS
n/a
Number of Employees
n/a
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N

Award Totals

PROGRAM/PHASE
AWARD AMOUNT ($)
NUMBER OF AWARDS
SBIR Phase I
$446,968.00
7
SBIR Phase II
$2,418,577.00
4
Chart code to be here

Award List

  1. DEVELOPMENT OF AN IN VITRO HUMAN BLOOD-BRAIN BARRIER

    Amount: $497,474.00

    THIS PROJECT WILL DEVELOP A WORKING IN VITRO BLOOD-BRAIN BARRIER MODEL WITH ENDOTHELIAL CELLS ISOLATED FROM HUMAN BRAIN MICROVASCULATURE. THIS MODEL WILL ALLOW RAPID ASSESSMENT OF THE EFFICACY OF DRUG ...

    SBIR Phase II 1991 Department of Health and Human Services
  2. DELIVERY OF NERVE GROWTH FACTOR TO THE BRAIN

    Amount: $422,381.00

    NERVE GROWTH FACTOR (NGF) HAS BEEN SHOWN IN VITRO AND IN VIVO TO SUPPORT THE GROWTH OF BASAL FOREBRAIN CHOLINERGIC NEURONS. IN ALZHEIMER'S DISEASE, THESE CELLS UNDERGO SIGNIFICANT DEGENERATIVE CHANGES ...

    SBIR Phase II 1992 Department of Health and Human Services
  3. ANTIBODIES THAT REVERSIBLY OPEN THE BLOOD-BRAIN BARRIER

    Amount: $49,595.00

    THIS RESEARCH PROJECT WILL DEVELOP A MONOCLONAL ANTIBODY-BASED SYSTEM TO REVERSIBLY PERMEABILIZE THE BLOOD-BRAIN BARRIER (BBB) TO BLOOD-BORNE THERAPEUTICS. SUCH ANTIBODIES ALSO MAY SERVE AS CARRIER MO ...

    SBIR Phase I 1992 Department of Health and Human Services
  4. Gene Therapy of Midbrain Dopamine Circuits

    Amount: $748,722.00

    Recombinant adeno-associated viral (rAAV) vectors are to be developed for transgene delivery to thenervous system (CNS). In particular, we are engineering rAAVs designed to transduce an expression cat ...

    SBIR Phase II 1997 Department of Health and Human Services
  5. N/A

    Amount: $99,193.00

    N/A

    SBIR Phase I 2000 Department of Health and Human Services
  6. N/A

    Amount: $0.00

    N/A

    SBIR Phase I 2001 Department of Health and Human Services
  7. N/A

    Amount: $750,000.00

    N/A

    SBIR Phase II 2001 Department of Health and Human Services
  8. Novel, sustained-release naltrexone for opiate abuse

    Amount: $98,980.00

    DESCRIPTION: While opiate agonists can be effective for treating abusers, they are. inappropriate in many circumstances. The opiate antagonist naltrexone (NTX) has been approved by the ...

    SBIR Phase I 2001 Department of Health and Human Services
  9. DEVELOPMENT OF AN IN VITRO HUMAN BLOOD-BRAIN BARRIER

    Amount: $50,000.00

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
  10. Gene Therapy of Midbrain Dopamine Circuits

    Amount: $100,000.00

    N/A

    SBIR Phase I 1995 Department of Health and Human Services

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