Rapid detection of food borne pathogenic bacteria

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$956,159.00
Award Year:
2004
Program:
SBIR
Phase:
Phase I
Contract:
1R43AI060274-01
Award Id:
71255
Agency Tracking Number:
AI060274
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
1 FIELDSTONE LN, OCEAN, NJ, 07712
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
SIMON BYSTRYAK
(973) 575-8484
SBYSTRYAK@AOL.COM
Business Contact:
SIMON BYSTRYAK
(609) 835-8352
SBYSTRYAK@AOL.COM
Research Institute:
n/a
Abstract
DESCRIPTION (provided by applicant): The objective of this proposal is to develop an ultrasound particle agglutination (UPA) method for determination of pathogenic bacteria Escherichia coli O157:H7 and Listeria monocytogenes in body fluids, food and environmental samples. The UPA assay is based on the use of ultrasound to significantly increase the sensitivity and reduce time of conventional particle agglutination immunoassay. Ultrasound waves are used for both accelerating and monitoring of the agglutination process. The effective testing of bacteria requires methods of analysis that meet a number of challenging criteria. Bacterial detection methods have to be rapid and very sensitive since the presence of even a single pathogenic organism in the body or food may be an infectious dose. The immunoassay we propose to develop will be implemented in a simple, portable and inexpensive device based on the novel patented cylindrical resonator technology. Significantly, the method can be easily adapted to detect other target objects. Preliminary studies confirmed feasibility of the major innovative components of the proposed technology and it is shown that the new method has significant commercial and scientific potential.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government