TISSUE CULTURE MEDIA ARE CURRENTLY SUPPLIED IN STERILE LIQUID AND NONSTERILE POWDERED FORMS.

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1985
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
3181
Agency Tracking Number:
3181
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
908 Niagara Falls Blvd., N. Tonawanda, NY, 14120
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
DONALD E. TARTOCK
PRINCIPAL INVESTIGATOR
(716) 695-1020
Business Contact:
() -
Research Institute:
n/a
Abstract
TISSUE CULTURE MEDIA ARE CURRENTLY SUPPLIED IN STERILE LIQUID AND NONSTERILE POWDERED FORMS. THERE IS A NEED TO DEVELOP STERILE POWDERED MEDIA. ALTHOUGH THE LIQUID FORM PROVIDES CONVENIENCE, IT HAS SEVERAL DRAWBACKS: SHORT SHELF LIFE, BATCH-TO-BATCH VARIABILITY, VULNERABILITY TO TEMPERATURE EXTREMES, CONTAINER DAMAGE AND CONTAMINATION, COSTLY REFRIGERATED STORAGE, AND HIGH UNIT PURCHASING AND TRANSPORTATION COSTS. USE OF POWDERED MEDIA RESOLVES THESE DEFICIENCIES. HOWEVER, POWDERED MEDIA REQUIRE STERILIZATION. PRESENT METHODS, USING EITHER AUTOCLAVING OR FILTRATION OF SOLUBILIZED POWDER, ALSO HAVE SERIOUS DISADVANTAGES, SUCH AS HEAT LABILITY OF CERTAIN COMPONENTS, AND FILTER MEMBRANE FAILURE. CHEMICAL STERILANTS HAVE ALSO PROVEN UNSATISFACTORY. PHASE I FUNDS ARE SOUGHT TO EXAMINE THE FEASIBILITY OF RENDERING THESE POWDERS STERILE. THESE MEDIA, WHICH WOULD BE PACKAGED IN A UNIQUELY CONSTRUCTED, LIGHT-WEIGHT CONTAINER, WOULD BE STABLE FOR SEVERAL YEARS OVER A WIDE TEMPERATURE RANGE. INITIAL STUDIES WOULD INCLUDE STERILIZATION METHODOLOGY, MICROBIAL EVALUATION, CONTAINER DEVELOPMENT, AND PERFORMANCE TESTING OF THE MEDIA. ENTHUSIASTIC RESPONSE TO THIS CONCEPT HAS BEEN RECEIVED FROM COMMERCIAL INTERESTS, BOTH DOMESTIC AND FOREIGN, WITH PARTICULAR POTENTIAL SEEN FOR FOREIGN TRADE.

* information listed above is at the time of submission.

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