DEVELOPMENT OF A CONTROLLED-ENVIRONMENT CHAMBER

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1987
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
7115
Agency Tracking Number:
7115
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
53 East Rogues Path, Huntington, NY, 11746
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
GARY R PAPAS
(516) 673-3333
Business Contact:
() -
Research Institution:
n/a
Abstract
THE LONG-TERM OBJECTIVE IS TO DEVELOP A MECHANICAL DEVICE THAT WILL PROVIDE COMPLETE ENVIRONMENTAL CONTROL (TEMPERATURE, PRESSURE, HUMIDITY, STERILITY, PH, GASEOUS ATMOSPHERE, AND LIGHT RAYS) OF BIOLOGICAL OR INDUSTRIAL SPECIMENS UNDER MICROSCOPIC EXAMINATION. CONTROLS WILL BE MAINTAINED EVEN DURING PERIODS OF PHYSICAL MANIPULATION OF THE SPECIMEN AND DURING MICROSCOPIC OBSERVATION THROUGH OPTICALLY CLEAR LENSES INHERENT IN THE DESIGN OF THE DEVICE. AMERICAN BOREMENE, INC. WILL WORK WITH THE COLD SPRING HARBOR LABORATORY TO DEVELOP THIS DEVICE. THE AIM IS TO DEVELOP A FUNCTIONAL DEVICE FROM A PROTOTYPE. SPECIFICALLY,THE ENVIRONMENTALLY CONTROLLED CHAMBER WILL BE USED FOR THE MICROINJECTION OF SPECIMENS WITHOUT COMPROMISING THE INTEGRITY OF THE SPECIMEN OR THE SAFETY OF THE RESEARCHER. THE METHODOLOGY WILL INCLUDE A DESIGN BASED ON MECHANICAL ENGINEERING AND PHYSICAL PRINCIPLES. EXISTING TECHNOLOGY AND INPUT FROM THE BIOMEDICAL SECTOR WILL BE CONSIDERED. THE DEVICE WILL BE TESTED AS TO ITS ABILITY TO MAINTAIN AN ENVIRONMENT AGAINST CURRENT LABORATORY TECHNIQUES WITH EXPERIMENTS INVOLVING THE MICROINJECTION OF LIVING TISSUE CULTURE CELLS. NO TECHNOLOGY EXISTS THAT PROVIDES FOR COMPLETE ENVIRONMENTAL CONTROL IN AN ECONOMICAL FORMAT AND CAN BE EASILY MANAGED ON THE STAGE OF A MICROSCOPE. COMMERCIAL APPLICATIONS THAT WILL RESULT FROM SUCCESSFUL RESEARCH INCLUDE AN INCREASE IN THE ACCURACY AND EFFICIENCY OF EXPERIMENTS REQUIRING ENVIRONMENTAL CONTROL, A MEANS OF PROTECTING RESEARCHERS FROM HOSTILE ORGANISMS OR NOXIOUS MATERIALS, AN IMPROVEMENT IN THE SUCCESS RATE OF HUMAN IN VITRO FERTILIZATION, AND AN ENERGY COST REDUCTION DURING PETROLEUM DISTILLATION.

* information listed above is at the time of submission.

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