Data System for High Speed Chromatography

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$749,994.00
Award Year:
1997
Program:
SBIR
Phase:
Phase II
Contract:
1 R43 GM53372-01,
Agency Tracking Number:
29468
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Analytica Of Branford, Inc.
29 Business Park Drive, Branford, CT, 06405
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
James Boyle
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
We will develop a high speed data system which uses a time-of-flight mass spectrometer (TOF-MS) asmass separation device and species detector. This data system will take advantage of the temporal spmass spectrometry to rapidly compute and display either liquid chromatography (LC) or capillary elecusing both Electrospray and Atmospheric Pressure Chemical Ionization (APCI) as inlet systems. 'Standand presentation will be performed, including ion chromatograms and both raw and averaged mass spectvirtue of the statistically significant numbers of spectra which one can generate using TOF-MS as adetector, other multi-parametric relationships will also be computed and presented. The data systemfour individual elements: a data acquisition module, a data storage module, high speed data reductiodata presentation module. A prototype data system including all of the above modules will be designetested in Phase I. This system will possess rudimentary real-time computational abilities which willPhase II studies.

* information listed above is at the time of submission.

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