NANOELECTRODE ENSEMBLES FOR NEUROCHEMICAL ANALYSIS

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$100,000.00
Award Year:
2001
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
54604
Agency Tracking Number:
1R43MH062846-01
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
1684 S RESEARCH LOOP, STE 518, TUCSON, AZ, 85710
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
AYYASAMY ARUCHAMY
() -
Business Contact:
(520) 546-6944
AMSEN@AZSTARNET.COM
Research Institute:
n/a
Abstract
DESCRIPTION: Nanoelectrode ensembles for neurochemical analysis are proposed. The proposed neurochemical probe can provide high performance measurements of neurochemical species that can help to reduce the burden of human illness and dysfunction from brain neuro-system causes and to understand each of these elements and how they interrelate. Electrochemical voltammetry has shown great promise for direct measurements of a variety of neurochemical species in neurosystems, however, the existing single probe microelectrodes have limitations that are not suitable for high performance voltammetric measurements. This program seeks to develop nano-meter scale electrode ensembles that are significantly faster, more sensitive, and reliable than existing microelectrodes. A novel template synthesis approach will be used to prepare nanoelectrode ensembles, and the innovation will focus on nano-engineering of the electrode structure that can provide advantages from the engineered nanostructure. The proposed nanoelectrode ensembles are expected to have significantly enhanced interfacial diffusivities and reduced double-layer capacitance enabling high speed measurements with low detection limits and high selectivity. During Phase I, AMSEN Technologies will demonstrate the proof-of-concept of such an electrode ensemble. The proposed innovation can be extremely useful for neurochemical analysis in applications where sensitive, selective, fast, and highly localized detection and monitoring of neurotransmitters are needed. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

* information listed above is at the time of submission.

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