Ultraviolet Light Devices for Vitamin D

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R41AG024061-01A1
Agency Tracking Number: AG024061
Amount: $164,498.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 2003
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
352 WEST 1060 SOUTH, 352 WEST 1060 SOUTH, Orem, UT, 84058
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 (801) 226-2370
Business Contact
Phone: (801) 226-2370
Research Institution
 715 ALBANY ST, 560
BOSTON, MA, 02118
 Nonprofit college or university
DESCRIPTION (provided by applicant): Vitamin D deficiency is now recognized as a significant health problem for middle-aged and older adults. Vitamin D deficiency exacerbates osteoporosis and causes the bone disease, osteomalacia. Vitamin D deficiency increases risk of skeletal fractures. It is well known that the ultraviolet B portion of the solar spectrum is responsible for the cutaneous production if vitamin D3. It has been estimated that approximately 90 to 95% of most people's vitamin D requirement comes from their casual exposure to sunlight. However, people above the age of 50 years do not get adequate exposure to sunlight placing them at risk for vitamin D deficiency. The goal of this program is to determine the feasibility of developing ultraviolet B light sources that can be used in a nursing home setting or in an individual home for promoting the cutaneous production of vitamin D3. This will be accomplished by using a whole body ultraviolet B light source and a portable partial body ultraviolet B home device unit. The goal will be to test the effect of exposure to varying doses of whole body and partial body ultraviolet B radiation from these prototype commercial devices to determine their effect on raising the blood level of vitamin D and 25-hydroxyvitamin D, the major circulating form of vitamin D that is used to determine the vitamin D status. This study addresses an issue crucial to the successful commercial development of ultraviolet B radiation sources that can be placed in nursing homes or in an individual home for the therapeutic purpose of producing vitamin D3.

* Information listed above is at the time of submission. *

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