Non-Invasive Ultrasonic Intracranial Pressure Measurement

Award Information
Agency:
Department of Defense
Branch
Defense Advanced Research Projects Agency
Amount:
$98,148.00
Award Year:
2010
Program:
SBIR
Phase:
Phase I
Contract:
W31P4Q-10-C-0060
Award Id:
96681
Agency Tracking Number:
09SB2-0066
Solicitation Year:
n/a
Solicitation Topic Code:
DARPA 09-003
Solicitation Number:
n/a
Small Business Information
9500 Innovation Drive, Manassas, VA, 20110
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
945837219
Principal Investigator:
John Sevick
Principal Investigator
(703) 368-6107
john.sevick@progeny.net
Business Contact:
Christine Sigety
Manager of Business Support
(703) 368-6107
csigety@progeny.net
Research Institution:
n/a
Abstract
Traumatic Brain Injury (TBI) is the leading cause of death and disability for ages 1 to 44. TBI results in 50,000 deaths, 90,000 survivors suffering permanent neurological disabilities, and $40B in health care costs annually. Insurgents' use of suicide bombers and IEDs has sharply increased the proportion of TBIs suffered by American troops, making it the "signature wound" in recent conflicts. TBI is difficult to diagnose, treat, and monitor in the field, with no external indication of the internal brain injuries. Rapid detection and treatment of TBI is critical in preventing further damage or death. Computerized axial tomography (CT) is the "gold standard" non-invasive method to determine the degree of cerebral injury, but is not suitable for field. Elevated Intracranial Pressure (ICP), above 20mm HG, is often the most direct, initial result of TBI. However, traditional invasive ICP measurements are also not possible in the field. In conjunction with Virginia Commonwealth University Medical System, Progeny proposes to investigate three non-invasive methods to measure ICP: Ultrasonic image of the optical nerve sheath diameter, Intra-ocular pressure, and a novel ultrasonic sound attenuation technique. Phase I will include prototype data collection system development for deployment in Phase II ICU and ED patient studies.

* information listed above is at the time of submission.

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