3-D SURFACE TEXTURED PLATINUM ELECTRODE/GLUCOSE SENSOR

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$41,598.00
Award Year:
1989
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
11453
Agency Tracking Number:
11453
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
6554 Beechwood Dr, Independence, OH, 44131
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
() -
Business Contact:
() -
Research Institute:
n/a
Abstract
THIS PROGRAM IS RELATED TO THE DEVELOPMENT OF A PLATINUM-POLYSTYRENE ELECTRODE WITH TEXTURED SURFACE FOR A SUBCUTANEOUS ELECTROCATALYTIC SENSOR. THE SUBCUTANEOUS SENSOR HAS LOWER RISKS COMPARED TO AN INTRAVENOUS SENSOR, SOIT IS CONSIDERED FOR LONG-TERM MONITORING PURPOSES. IT HAS BEEN DEMONSTRATED THAT TEXTURED SURFACES ARE FAVORABLE FOR IMPLANTATION TO THE SOFT TISSUE DUE TO BETTER VASCULARIZATION IN THE VICINITY OF THE IMPLANT AND LOWER THICKNESS OF FIBROUS CAPSULE COMPARED TO SMOOTH-SURFACE IMPLANTS. TEXTURED ELECTRODES WILL BE DEVELOPED OUT OF PLATINUM BLACK SUSPENDED IN POLYSTYRENE. THIS KIND OF MATERIAL WILL ALLOW FOR THE ELECTRODE'S FABRICATION BY A THERMOCOMPRESSION MOLDING TECHNIQUE. THE STUDIES WILL INCLUDE OPTIMIZATION OF PLATINUM CONTENT IN SUSPENSION AND ELECTRODE STABILITY TESTS. IN PHASE II, A CLINICAL PROTOTYPE OF THE SUBCUTANEOUS ELECTROCATALYTIC SENSOR WILL BE DEVELOPED. THESTUDIES IN PHASE II WILL ALSO INCLUDE THE INTEGRATION PROCEDURE OF THE TEXTURED SENSING ELECTRODE WITH THE SENSOR'S OTHER ELEMENTS AND EXTENSIVE ANIMAL TESTS.

* information listed above is at the time of submission.

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