Gridless Simulation of Flow-MPHV Interaction

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$1,209,823.00
Award Year:
2007
Program:
SBIR
Phase:
Phase II
Contract:
9R44RR024300-02A1
Award Id:
71012
Agency Tracking Number:
HL078045
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
APPLIED SCIENTIFIC RESEARCH, 1800 E GARRY AVE, STE 214, SANTA ANA, CA, 92705
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
046276809
Principal Investigator:
ADRINGHARAKHANI
(949) 752-7545
ADRIN@APPLIED-SCIENTIFIC.COM
Business Contact:
ADRINGHARAKHANI
() -
adrin@Applied-Scientific.com
Research Institute:
n/a
Abstract
DESCRIPTION (provided by applicant): The objective of this project is to develop a CFD software for the grid-free simulation and analysis of the complex dynamics of the Fluid-Structure Interaction (FSI) associated with Mechanical Prosthetic Heart Valve (MP HV) systems as they respond to physiologically realistic 3-D pulsatile flow. The final product will be the first commercially available grid-free virtual MPHV test chamber, which can be used by scientists and heart valve designers, for example, to inve stigate new hypotheses on the unsteady hemodynamic aspect of cardiac physiology; to perform parametric studies in order to design new or to improve existing prosthetic valves; or to establish criteria for MPHV implantation (e.g. orientation) under which va lve performance will be acceptable. The specific research aims are to (1) develop accurate methods for fluid force calculations on the valves and implement the coupling between the fluid and the valve; (2) implement computational techniques to further impr ove adaptivity, user friendliness and CPU turn around times; and (3) validate the resultant software using physiologically realistic test cases.

* information listed above is at the time of submission.

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