Neuromonitoring of Traumatic Brain/blast Injury

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-10-C-0060
Agency Tracking Number: O093-H06-3092
Amount: $99,983.00
Phase: Phase I
Program: SBIR
Awards Year: 2010
Solitcitation Year: 2009
Solitcitation Topic Code: OSD09-H06
Solitcitation Number: 2009.3
Small Business Information
Quantum Applied Science and Research Inc
5764 Pacific Center Blvd, Suite 107, San Diego, CA, 92121
Duns: 016541711
Hubzone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Konstantine Ermolaev
 Research Scientist
 (858) 228-1093
 Konstantine@quasarusa.com
Business Contact
 Tracey Bennett-Wrightson
Title: Director of Operations
Phone: (858) 412-1800
Email: tracey@quasarusa.com
Research Institution
N/A
Abstract
Brain related injuries are a major cause of disability, death and economic cost to modern society, and are a distinguishing feature of the US military’s recent conflicts. Rheoencephalography (REG) and Electroencephalography (EEG) are non-invasive, real-time measurements compatible with use in a miniaturized portable system to provide detailed information on the cerebrovascular and neurological status of a patient during evacuation from the battlefield and in the hospital during recovery. Quantum Applied Science and Research (QUASAR) has extensive experience in developing EEG and other bioelectric sensing systems for convenient, real-world use, including in battlefield settings. On Phase I of this program, QUASAR will apply its technology for no-prep dry electrode systems to develop an overall design and specifications for an REG/EEG system that will detect changes in the autoregulation of cerebral blood flow and alarm if the lower limit of autoregulation is reached. Similarly, the system will detect and alarm on failure of neuronal synaptic transmission indicating insufficient cerebral blood flow. In addition, the system will measure indications of vasospasm, and increase intracranial pressure. Phase II of the program will build the specified system, together with testing in human and animal studies.

* information listed above is at the time of submission.

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