APT THERAPEUTICS, INC.

Basic Information

4041 Forest Park Avenue
SAINT LOUIS, MO, 63108-3213

Company Profile

n/a

Additional Details

Field Value
DUNS: 192266141
Hubzone Owned: N
Socially and Economically Disadvantaged: N
Woman Owned: N
Number of Employees: n/a


  1. Optimized IL2-based Therapy for Type 1 Diabetes

    Amount: $298,486.00

    DESCRIPTION provided by applicant Type diabetes is an immune mediated disease in which insulin producing beta cells are destroyed resulting in life long dependence on exogenous insulin The numb ...

    SBIR Phase I 2015 Department of Health and Human Services National Institutes of Health
  2. Low-dose IL-2-based Immunomodulatory Therapy for PAH

    Amount: $297,410.00

    DESCRIPTION provided by applicant Despite evidence that inflammatory mechanisms initiate and complicate pathophysiology in pulmonary arterial hypertension PAH no strategies have been developed ...

    SBIR Phase I 2015 Department of Health and Human Services National Institutes of Health
  3. Human Apyrase Therapy for Diabetic Neuropathic Pain

    Amount: $299,793.00

    DESCRIPTION provided by applicant Neuropathic pain such as diabetic neuropathic pain DNP can be difficult to treat with only of patients achieving meaningful andgt pain relief Cu ...

    SBIR Phase I 2015 Department of Health and Human Services National Institutes of Health
  4. Manufacturing of Growth Factors to Enable Cardiopoietic Stem Cell Therapy for Hea

    Amount: $224,139.00

    DESCRIPTION (provided by applicant): Cardiopoietic cell therapy significantly improved left ventricular function, blunted pathological remodeling, and functional outcomes in animal models and Phase I/ ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. Low-dose IL2-based Immunomodulatory therapy for Stroke

    Amount: $224,879.00

    DESCRIPTION (provided by applicant): It has been recently shown that CD4+ and CD8+ T lymphocytes are critically involved in the collateral brain injury and neurological deficit associated with experim ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Magnetic Flow Sorter for Pancreatic Islet Isolation

    Amount: $288,298.00

    DESCRIPTION (provided by applicant): Bone metastasis is common in patients with advanced breast, prostate, and lung cancers as these tumors have a remarkable ability to metastasize to bone. Two-thirds ...

    SBIR Phase I 2013 Department of Health and Human Services
  7. Adjunctive Use of Apyrase to Fibrinolytic Therapy

    Amount: $1,307,456.00

    DESCRIPTION (provided by applicant): Acute myocardial infarction is the leading cause of death in most industrialized nations. The estimated annual incidence in the US is 865,000 events, with ST-segm ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. Prevention of Vein Graft Intimal Hyperplasia with Optimized Human Apyrase

    Amount: $281,598.00

    DESCRIPTION (provided by applicant): The saphenous vein is the most commonly used graft for coronary artery bypass and peripheral bypass surgery, but has poor patency. 15-20% grafts fail in the first ...

    SBIR Phase I 2012 Department of Health and Human Services
  9. Combination Treatment of tPA and Apyrase for Stroke

    Amount: $1,107,150.00

    DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy for acute ischemic stroke which is a leading cause of death and disability with almost no effective therapy for ...

    SBIR Phase II 2010 Department of Health and Human Services
  10. Combination Therapy of Aspirin and Apyrase for Stroke

    Amount: $287,622.00

    DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy for acute ischemic stroke which is a leading cause of death and disability with almost no effective therapy for ...

    SBIR Phase I 2010 Department of Health and Human Services

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