BioPhalanx, a hand portable discrete monolithic microarray biothreat detector

Award Information
Agency: Department of Homeland Security
Branch: N/A
Contract: NBCHC070088
Agency Tracking Number: 0523004
Amount: $999,201.46
Phase: Phase II
Program: SBIR
Awards Year: 2011
Solicitation Year: 2005
Solicitation Topic Code: H-SB05.2-001
Solicitation Number: FY05.2
Small Business Information
Arcxis Biotechnologies
18858 Carlton Ave, Castro Valley, CA, 94546-2908
DUNS: 171081529
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Jay West
 CTO and Senior Director of Research
 (925) 461-1300
 jwest@arcxis.com
Business Contact
 Jay West
Title: Acting CTO and consultant
Phone: (925) 766-3693
Email: khukari@arcxis.com
Research Institution
N/A
Abstract
The following proposal describes the planned effort of Arcxis Biotechnologies in the development of a rapid portable biosensor, we call BioPhalanxTM. During the Phase I SBIR project, we developed an alpha prototype for rapid point-of-care/point-of-incident instrument for the discrimination of biological agents. Our main overarching technical goal is to eliminate the need for PCR based detection, while retaining the necessary sensitivity, selectivity, rapid response, and robustness required in rugged field environments. Having completed the Phase I effort, we confidently believe based on the data generated that we have demonstrated the feasibility, in terms of sensitivity, selectivity, rapid response of the assay approach. Further the externally deployed prototype system demonstrated instantaneous detection of threat genes for B. Anthracis. The primary goals of this proposed effort are to 1) increase the sensitivity of the device, 2) produce the pre-production prototype that will be deployed to between at least five customers for the detection of no less than 20 CDC category A, B, C viruses and bacteria, and 3) develop a manufacturable system that will allow cost-effective production and sales of the BioPhalanx.

* information listed above is at the time of submission.

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