High Multiplexing Liquid Array Assay Platform

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$99,999.00
Award Year:
2009
Program:
SBIR
Phase:
Phase I
Contract:
1R43EB008616-01A1
Award Id:
93741
Agency Tracking Number:
EB008616
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
ARRAYOMICS, INC., 9909 HIBERT ST, STE A, SAN DIEGO, CA, 92131
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
140695847
Principal Investigator:
DAVIDROTHWARF
(858) 245-2435
DROTHWARF@ARRAYOMICS.COM
Business Contact:
CHRISTOPHERHEROLD
() -
drothwarf@arrayomics.com
Research Institute:
n/a
Abstract
DESCRIPTION (provided by applicant): The aim of this project is to expand the capabilities of a novel liquid array' platform, based on Encoded Sortable Particle (ESP) technology to make it cost and performance compatible with high multiplex assays. ESPs are optically-encoded microfabricated particles that can be manipulated using magnetic force. We will adapt our ESP-based liquid array system, which has already been successfully applied in the low multiplex space, to accommodate assays of 100,000-plex or more. ESP technology has broad applicability and should be a valuable tool in the diagnosis, prognosis, and characterization of a variety of disease states, including cancer, heart disease, arthritis and inflammatory diseases, kidney disease, liver disease , allergic responses, and infectious diseases (e.g. HIV). PUBLIC HEALTH RELEVANCE: ESP technology as applied to the high multiplex assay space will provide a broad platform for many different kinds of assays. The ESP platform is intrinsically versatile, an d has the potential to be used in basic biomedical research, as well as high- throughput discovery and clinical diagnostics. The ability to control the particles magnetically (in a manner significantly different from magnetic beads) is a significant advant age. This technology should be useful in the diagnosis and prognosis of a variety of disease states, including cancer, heart disease, arthritis and inflammatory diseases, kidney disease, and infectious diseases (e.g. HIV).

* information listed above is at the time of submission.

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