High Multiplexing Liquid Array Assay Platform

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R43EB008616-01A1
Agency Tracking Number: EB008616
Amount: $99,999.00
Phase: Phase I
Program: SBIR
Awards Year: 2009
Solitcitation Year: 2009
Solitcitation Topic Code: N/A
Solitcitation Number: PHS2009-2
Small Business Information
ARRAYOMICS, INC.
ARRAYOMICS, INC., 9909 HIBERT ST, STE A, SAN DIEGO, CA, 92131
Duns: 140695847
Hubzone Owned: Y
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 DAVID ROTHWARF
 (858) 245-2435
 DROTHWARF@ARRAYOMICS.COM
Business Contact
 CHRISTOPHER HEROLD
Phone: (858) 578-0977
Email: drothwarf@arrayomics.com
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): The aim of this project is to expand the capabilities of a novel liquid array' platform, based on Encoded Sortable Particle (ESP) technology to make it cost and performance compatible with high multiplex assays. ESPs are optically-encoded microfabricated particles that can be manipulated using magnetic force. We will adapt our ESP-based liquid array system, which has already been successfully applied in the low multiplex space, to accommodate assays of 100,000-plex or more. ESP technology has broad applicability and should be a valuable tool in the diagnosis, prognosis, and characterization of a variety of disease states, including cancer, heart disease, arthritis and inflammatory diseases, kidney disease, liver disease, allergic responses, and infectious diseases (e.g. HIV). PUBLIC HEALTH RELEVANCE: ESP technology as applied to the high multiplex assay space will provide a broad platform for many different kinds of assays. The ESP platform is intrinsically versatile, and has the potential to be used in basic biomedical research, as well as high- throughput discovery and clinical diagnostics. The ability to control the particles magnetically (in a manner significantly different from magnetic beads) is a significant advantage. This technology should be useful in the diagnosis and prognosis of a variety of disease states, including cancer, heart disease, arthritis and inflammatory diseases, kidney disease, and infectious diseases (e.g. HIV).

* information listed above is at the time of submission.

Agency Micro-sites

US Flag An Official Website of the United States Government