You are here

Development of Technologies that Address the Complex Architecture of the Face During the Treatment of Severe Facial Burn Injury

Award Information
Agency: Department of Defense
Branch: Defense Health Agency
Contract: W81XWH-14-C-0022
Agency Tracking Number: H2-0073
Amount: $999,656.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: DHP13-016
Solicitation Number: 2013.2
Timeline
Solicitation Year: 2013
Award Year: 2015
Award Start Date (Proposal Award Date): 2015-05-14
Award End Date (Contract End Date): 2017-10-17
Small Business Information
Richard Dean Research Building, Suite 168
Winston-Salem, NC 27101
United States
DUNS: 000000000
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Luke Burnett
 (336) 202-1307
 luke.burnett@keranetics.com
Business Contact
 Kim Westmoreland
Title: Dr.
Phone: (336) 725-0621
Email: kim.westmoreland@keranetics.com
Research Institution
N/A
Abstract

Burn injuries, particularly those to the face, present a number of functional and psychological challenges that arise from scarring and related contracture. A major goal of trauma and burn surgeons is to prevent scarring and improve grafting technologies given the complexity of facial topography. This project seeks to optimize and finalize a prototype of a 3D printed keratin facemask capable of delivering drugs capable of inhibiting scar formation. This will be accomplished by first optimizing the formulation through a series of in vitro tests, screening optimized formulations in a small thermal burn wound model in pigs, and confirming efficacy of the selected construct in a large thermal burn wound model in pigs. Additionally, a facemask prototype will be printed, and storage parameters will be determined. The resulting construct will be able to act as a long-term primary burn wound dressing that delivers a drug to prevent scarring as it naturally degrades, reducing the need for full, painful dressing changes and the risk of scarring and contracture in our Wounded Warriors.

* Information listed above is at the time of submission. *

US Flag An Official Website of the United States Government