SWALLOWABLE ELECTRODES FOR TEMPORARY CARDIAC PACING

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$500,000.00
Award Year:
1985
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Award Id:
1507
Agency Tracking Number:
1507
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
5757 North Sheridan Road, Suite 13a, Chicago, IL, 60660
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Janice M. Jenkins
Senior Scientist
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
THE LONG TERM OBJECTIVE OF THIS PROJECT IS THE DEVELOPMENT AND MARKETING OF EASILY SWALLOWED ELECTRODES FOR TEMPORARY TRANSESOPHAGEAL CARDIAC PACING. THIS "PILL ELECTRODE" CAN REPLACE CARDIAC CATHETERIZATION IN A VARIETY OF DIAGNOSTIC AND THERAPEUTIC APPLICATIONS, INCLUDING INITIATION AND/OR TERMINATION OF TACHYCARDIAS, SHORT TERM MAINTENANCE OF ADEQUATE RATE IN SINUS BRADYCARDIA, ACCELERATION OF RATE TO PRODUCE STRESS DURING ECHOCARDIOGRAPHIC OR RADIONUCLIDE STUDIES OF VENTRICULAR FUNCTION. WITH TRANSESOPHAGEAL INSTEAD OF CATHETER PACING, THESE BECOME OUT-PATIENT PROCEDURES WITH A GREATLY REDUCED COMPLEXITY AND COST. THE SPECIFIC AIMS FOR PHASE I ARE 1) DETERMINE AN OPTIMAL DESIGN FOR THE BIPOLAR TRANSESOPHAGEAL PACING ELECTRODE, 2) IMPLEMENT THE DESIGN IN AN ELECTRODE THAT CAN BE ENCLOSED IN AN ORDINARY PHARMACEUTICAL CAPSULE LIKE THE PRESENT ARZCO PILL ELECTRODE FOR ESOPHAGEAL ELECTROCARDIOGRAPHY, 3) DEVELOP NEW ELECTRONIC CIRCUITS FOR THE SPECIAL NONPOLARIZING STIMULATOR TO BE USED IN THIS HIGH-CURRENT, SWITCHED PACING/RECORDING APPLICATION, 4) FABRICATE A FLEXIBLE, ULTRA-THIN SILICONE RUBBER SHEATH TO USE WITH THE PILL ELECTRODE TO IMPROVE FIXATION AND PROVIDE FOR DELIVERY OF AIR AND LOCAL ANAESTHETIC, AND 5) DESIGN A CONTINUATION STUDY (PHASE II) WHICH WILL EVALUATE THE ELECTRODE/STIMULATOR SYSTEM UNDER CLINICAL CONDITIONS, CONCEIVE NEW CLINICAL APPLICATIONS, AND DEVELOP A MANUFACTURING AND MARKETING PLAN FOR WIDE UTILIZATION OF THE TECHNIQUE.

* information listed above is at the time of submission.

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