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Purpose The purpose of the Non-invasive Diagnostics in Gynecologic Health RFA is to support SBIR projects to small businesses using advanced technologies (e.g., bio-chips, microfluidics, and mobile technologies) to develop novel or improved diagnostic and/or screening approaches, tools, or devices for endometriosis, adenomyosis, and/or uterine fibroids. The ultimate goal of the program is to imp ...

TECHNOLOGY AREA(S): OBJECTIVE: This STTR aims to investigate feasibility of new materials and manufacturing methods for soft magnet technology with improved thermal performance, lower losses at high switching frequencies, and higher power ratings for use in for ultra-wide bandgap devices, and demonstrate feasibility of a prototype high-speed electric motors, transformer, or inductor leveraging the ...

TECHNOLOGY AREA(S): OBJECTIVE: TWISTED investigates approaches to providing trustworthy detachable solid-state storage devices. TWISTED results will identify commercialization opportunities for a DoD-acceptable Safe Memory Stick.DESCRIPTION: Detachable solid-state storage devices, a.k.a. memory sticks, have enjoyed increases in density and Input/Output data rates. Coupled to decreases in cost, con ...

TECHNOLOGY AREA(S): OBJECTIVE: The goal of GRIDMAPS is to enable critical long-term resilience by developing a power flow and connectivity modeling program that can: i) integrate data in real-time with the dynamic and potentially re-infected grid landscape as it undergoes incremental cyber clean up; ii) provide real time operational feedback; iii) create relevant data that can rapidly inform decis ...

TECHNOLOGY AREA(S): Bio Medical, Chem Bio DefenseOBJECTIVE: This SBIR would enhance detection of pathogens from complex samples by developing a high-throughput, low-cost, physiologically realistic model system that demonstrates human tissue hierarchy and cellular heterogeneity and, critically, is compatible with high-speed microfluidics.DESCRIPTION: Warfighters are travelers, continually exposed t ...

TECHNOLOGY AREA(S): Bio Medical, Chem Bio DefenseOBJECTIVE: Develop a rapid and cost-effective de novo synthetic DNA manufacturing capability.DESCRIPTION: There is a critical DoD need to be able to rapidly and efficiently synthesize highly accurate kilobase (kb) pair length DNA constructs for medical countermeasure and synthetic biology applications.Several DARPA programs and technologies (ex: Liv ...

TECHNOLOGY AREA(S): Bio Medical, Chem Bio DefenseOBJECTIVE: Apply artificial intelligence (AI) to accelerate the design of highly specific, engineered biomarkers for rapid virus detection.DESCRIPTION: This SBIR seeks to leverage AI technologies to accelerate the development of aptamer-based biosensors that specifically bind to biomolecular structures. Aptamers are short single-stranded nucleic aci ...

TECHNOLOGY AREA(S): OBJECTIVE: CHARIOT will develop revolutionary approaches for fast, efficient, and quantum-resistant cryptographic operations for Internet of Things (IoT) devices. Confidential communications, message integrity, group membership, and scalable key management must be demonstrated.DESCRIPTION: The exponential price/performance improvements in semiconductor technology stemming from ...

This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) proposing research for commercial development of novel cancer-relevant technologies. The proposed research projects are expected to focus on the development of highly-innovative technologies that improve molecular and/or cellular analysis of cancer ...

The Small Business Innovation Research (SBIR) program is a highly competitive program that encourages domestic small businesses to engage in Federal Research/Research and Development (R/R&D) that has the potential for commercialization. Through a competitive awards-based program, SBIR enables small businesses to explore their technological potential and provides the incentive to profit from its c ...