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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

Displaying 1 - 10 of 185 results
  1. RFA-HG-15-039 : Novel Nucleic Acid Sequencing Technology Development- Direct to Phase II (R44

    Release Date: 10-27-2015Open Date: 06-14-2016 Due Dates: Multiple Close Date: 08-07-2016

    Purpose This Funding Opportunity Announcement (FOA)  seeks Direct to Phase II R44 SBIR grant applications from small businesses to develop novel technologies that will enable at least one order of magnitude improvement in DNA sequencing, and practical methods for direct RNA sequencing.  Advances in genomics and more broadly in biomedical research have been greatly facilitated by signific ...

    SBIR Department of Health and Human Services
  2. Laboratory and Diagnostic Tools to Advance Microbiome-Brain Research (R43/R44)

    Release Date: 04-15-2016Open Date: 07-15-2016Due Date: 08-15-2016Close Date: 08-15-2016

    Background The complex and dynamic human microbiota profoundly affect human health and diseases in a variety of ways. Microbiota affect physiological processes including digestion, growth, immune defense and nervous systems. Mounting evidence indicates that components of the human microbiome change over time and are affected by a patient disease state and medication. It was also shown that microbi ...

    SBIR Department of Health and Human Services
  3. Improved Technologies and Ligands for Non-invasive Brain Imaging (R43/R44)

    Release Date: 04-12-2016Open Date: 07-17-2016Due Date: 08-17-2016Close Date: 08-17-2016

    Background A continuing impediment to the understanding and diagnosis of brain disorders is our limited ability to non-invasively visualize viruses, proteins, metabolites, and other molecules in the brain in vivo. Existing technology, such as Positron Emission Tomography (PET), Magnetic Resonance Spectroscopy (MRS), and Single-photon emission computed tomography (SPECT), are currently optimal only ...

    SBIR Department of Health and Human Services
  4. RFA-DA-17-010: Improved Technologies and Ligands for Non-invasive Brain Imaging (R41/R42)

    Release Date: 04-12-2016Open Date: 07-17-2016Due Date: 08-17-2016Close Date: 08-17-2016

    Background A continuing impediment to the understanding and diagnosis of brain disorders is our limited ability to non-invasively visualize viruses, proteins, metabolites, and other molecules in the brain in vivo. Existing technology, such as Positron Emission Tomography (PET), Magnetic Resonance Spectroscopy (MRS), and Single-photon emission computed tomography (SPECT), are currently optimal only ...

    STTR Department of Health and Human Services
  5. Laboratory and Diagnostic Tools to Advance Microbiome-Brain Research (R41)

    Release Date: 04-15-2016Open Date: 07-17-2016Due Date: 08-17-2016Close Date: 08-17-2016

    Background The complex and dynamic human microbiota profoundly affect human health and diseases in a variety of ways. Microbiota affect physiological processes including digestion, growth, immune defense and nervous systems. Mounting evidence indicates that components of the human microbiome change over time and are affected by a patient disease state and medication. It was also shown that microbi ...

    STTR Department of Health and Human Services
  6. RFA-ES-16-006: SBIR E-learning for HAZMAT and Emergency Response (R43/R44)

    Release Date: 06-28-2016Open Date: 07-29-2016Due Date: 08-29-2016Close Date: 08-29-2016

    This SBIR FOA focuses on the development of e-learning products that support the health and safety training of hazardous materials workers, emergency responders, and skilled support personnel, and supports the development of e-learning products that assist both students and instructors with a variety of delivery platforms. The following three areas describe the type of products that will be suppor ...

    SBIR Department of Health and Human Services
  7. PAR-13-346: HHS STTR PAR-13-346

    Release Date: 09-06-2013Open Date: 11-05-2013 Due Dates: Multiple Close Date: 09-07-2016

    Purpose The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and participating Institutes within the National Institutes of Health (NIH) encourage grant applications to address different and complementary research needs for the development of appropriate pediatric drug formulations in different age groups. This FOA also encourages the development and testin ...

    STTR Department of Health and Human Services
  8. PAR-13-345: HHS SBIR PAR-13-345

    Release Date: 09-06-2013Open Date: 11-05-2013 Due Dates: Multiple Close Date: 09-07-2016

    Purpose The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and participating Institutes within the National Institutes of Health (NIH) encourage grant applications to address different and complementary research needs for the development appropriate pediatric drug formulations in different age groups. This FOA also encourages the development and testing o ...

    SBIR Department of Health and Human Services
  9. PA-14-308: HHS STTR PA-14-308

    Release Date: 08-04-2014Open Date: 11-05-2014 Due Dates: Multiple Close Date: 09-07-2016

    Purpose The purpose of this initiative is to incentivize small businesses to generate new technologies and products for  delivering nucleic acids  into cells and tissues for the purpose of treatment or prevention of human disease.  Background There are thousands of rare diseases, and a substantial fraction of these are monogenic disorders, resulting from mutations in a single ...

    STTR Department of Health and Human Services
  10. PA-14-307: HHS SBIR PA-14-307

    Release Date: 08-04-2014Open Date: 11-05-2014 Due Dates: Multiple Close Date: 09-07-2016

    Purpose The purpose of this initiative is to incentivize small businesses to generate new technologies and products for  delivering nucleic acids  into cells and tissues for the purpose of treatment or prevention of human disease.  Background  There are thousands of rare diseases, and a substantial fraction of these are monogenic disorders, resulting from mutations in a s ...

    SBIR Department of Health and Human Services

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