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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. RFA-ES-22-004: SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed)

    Release Date: 04-26-2022Open Date: 06-20-2022Due Date: 07-20-2022Close Date: 07-21-2022

    This SBIR Funding Opportunity Announcement (FOA) focuses on the development of e-Learning health and safety training products from a variety of delivery methods to assist both students and instructors in the training and education process. Note that all products must be directly related to the health and safety training of workers exposed to hazardous materials (HAZMAT). Workers that may be expose ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. RFA-CA-22-025: SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)

    Release Date: 04-05-2022Open Date: 07-05-2022Due Date: 08-05-2022Close Date: 08-05-2022

    Purpose The Small Business Innovation Research (SBIR) Program is an important mechanism by which the National Institutes of Health (NIH) and other Federal agencies help bring innovative solutions to public health challenges. A major objective of the Federal SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of medi ...

    SBIRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
  3. RFA-CA-22-017: Small Business Transition Grant For Early Career Scientists (R42 Clinical Trial Not Allowed)

    Release Date: 03-21-2022Open Date: 07-22-2022Due Date: 08-22-2022Close Date: 08-23-2022

    Purpose Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI), National Institute of Biomedical Imaging and Bioengineering (NIBIB), and National Institute on Drug Abuse (NIDA) intend to support early-career academic scientists interested in transitioning to entrepreneurship while also supporting the transfer of technology from academic laboratories into small bu ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  4. 1: Clean and Safe Water

    Release Date: 06-15-2022Open Date: 06-15-2022Due Date: 08-23-2022Close Date: 08-23-2022

    Decentralized wastewater treatment (septic system) technologies for intentional non-potable reuse Technologies to process, sort and identify microplastics In-stream aquatic trash capture technologies Sensors to detect high priority contaminants of emergin ...

    SBIRPhase IEnvironmental Protection Agency
  5. 2: Air Quality & Climate

    Release Date: 06-15-2022Open Date: 06-15-2022Due Date: 08-23-2022Close Date: 08-23-2022

    Ambient air monitoring technology for air toxics Continuous Emission Monitoring System for metal HAPs Air monitoring technology for methane emissions from fugitive sources Technologies that reduce exposure to radon in buildings Technologies for improved r ...

    SBIRPhase IEnvironmental Protection Agency
  6. 3: Homeland Security

    Release Date: 06-15-2022Open Date: 06-15-2022Due Date: 08-23-2022Close Date: 08-23-2022

    Innovative technology solutions that build community resilience to disasters Miniaturized oil spill droplet size sensor for emergency response underwater vehicles 3 EPA SBIR 2022-2023 Phase I Solicitation Environmental Protection Agency ...

    SBIRPhase IEnvironmental Protection Agency
  7. 4: Circular Economy/Sustainable Materials

    Release Date: 06-15-2022Open Date: 06-15-2022Due Date: 08-23-2022Close Date: 08-23-2022

    Innovative technologies that help consumers prevent food waste in the acquisition, preparation, and storage of food Innovative technologies or materials that will improve the U.S. recycling system Innovative reduction, reuse, and recycling solutions to ad ...

    SBIRPhase IEnvironmental Protection Agency
  8. 5: Safer Chemicals

    Release Date: 06-15-2022Open Date: 06-15-2022Due Date: 08-23-2022Close Date: 08-23-2022

    PCB-free color Rubber anti-degradant technologies for tires and other rubber products that are lower concern for human health and the environment Innovative enhanced efficiency fertilizers 5 EPA SBIR 2022-2023 Phase I Solicitation Environmental Protection ...

    SBIRPhase IEnvironmental Protection Agency
  9. 6: Risk Assessment

    Release Date: 06-15-2022Open Date: 06-15-2022Due Date: 08-23-2022Close Date: 08-23-2022

    Software tools and machine-learning applications for systematic review in science assessment for chemical evaluation 6 EPA SBIR 2022-2023 Phase I Solicitation Environmental Protection Agency ...

    SBIRPhase IEnvironmental Protection Agency
  10. 1A: Decentralized wastewater treatment (septic system) technologies for intentional non-potable reuse

    Release Date: 06-15-2022Open Date: 06-15-2022Due Date: 08-23-2022Close Date: 08-23-2022

    Modular DNW technologies that intentionally reuse wastewater as an alternative to the conventional residential septic system. Proposed technologies will need to comply with future state level treatment requirements to protect public health. Ideally, technologies would be passive requiring minimal maintenance by homeowners or renters. Innovation is needed to make the technologies cheaper, easier to ...

    SBIRPhase IEnvironmental Protection Agency
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