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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. RFA-DA-19-014 : Loyalty and Reward-Based Technologies to Increase Adherence to Substance Use Disorder Pharmacotherapies (R43/R44- Clinical Trial Optional)

    Release Date: 09-19-2018Open Date: 11-14-2018Due Date: 12-14-2018Close Date: 12-14-2018

    Section I. Funding Opportunity Description Applications under this FOA are encouraged, but not required, to apply approaches and tools developed under the NIH Common Fund’s Science of Behavior Change (SOBC) Program. These include: use-inspired research on mechanisms of change at multiple levels of analysis; assays for self-regulation, interpersonal processes and stress that have eviden ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  2. RFA-DA-19-015 : Loyalty and Reward-Based Technologies to Increase Adherence to Substance Use Disorder Pharmacotherapies (R41/R42- Clinical Trial Optional)

    Release Date: 09-19-2018Open Date: 11-14-2018Due Date: 12-14-2018Close Date: 12-14-2018

    Section I. Funding Opportunity Description Applications under this FOA are encouraged, but not required, to apply approaches and tools developed under the NIH Common Fund’s Science of Behavior Change (SOBC) Program. These include: use-inspired research on mechanisms of change at multiple levels of analysis; assays for self-regulation, interpersonal processes and stress that have eviden ...

    STTR Department of Health and Human ServicesNational Institutes of Health
  3. PAR-16-410: Wearable Alcohol Biosensors SBIR (R43/R44)

    Release Date: 08-17-2016Open Date: 11-06-2016 Due Dates: Multiple Close Date: 04-04-2019

    Rapid advances are being made in wearable technology, including clothing, jewelry and other devices with broadly diverse functions that meet medical or consumer needs.  This FOA seeks applications from small businesses that propose to design and produce a non-invasive wearable device to monitor blood alcohol levels in real time. Alcohol detection technology for personal alcohol monitoring has ...

    SBIR Department of Health and Human Services
  4. PAR-18-204: Wearable Alcohol Biosensors SBIR (R43/R44 Clinical Trial Optional)

    Release Date: 11-28-2017Open Date: 03-05-2018 Due Dates: Multiple Close Date: 04-04-2019

    Rapid advances are being made in wearable technology, including clothing, jewelry and other devices with broadly diverse functions that meet medical or consumer needs.  This FOA seeks applications from small businesses that propose to design and produce a non-invasive wearable device to monitor blood alcohol levels in real time. Alcohol detection technology for personal alcohol monitoring ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  5. Small Business Alzheimer's Disease Research (R43/R44)

    Release Date: 02-01-2016Open Date: 03-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Alzheimer’s disease (AD) is the leading cause of dementia in those over the age of 65 and as many as 5 million Americans age 65 and older have AD.  As the population ages the number of people age 65 and older with AD is projected to increase between two and three fold by 2050 without a cure or prevention of the disease. AD is one of the most persistent and devastating dementing disorders of ...

    SBIR Department of Health and Human Services
  6. Small Business Alzheimer's Disease Research (R41/R42)

    Release Date: 02-01-2016Open Date: 03-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Alzheimer’s disease (AD) is the leading cause of dementia in those over the age of 65 and as many as 5 million Americans age 65 and older have AD.  As the population ages the number of people age 65 and older with AD is projected to increase between two and three fold by 2050 without a cure or prevention of the disease. AD is one of the most persistent and devastating dementing disorders of ...

    STTR Department of Health and Human Services
  7. PA-16-158 : New Technologies for the Glycosciences (R41/42)

    Release Date: 03-30-2016Open Date: 08-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Carbohydrates (or glycans) play roles in a wide range of biological functions and disease processes. Nearly all aspects of biology, including: a) protein folding; b) cell adhesion and trafficking; c) cell signaling, fertilization and embryogenesis; and d) pathogen recognition and immune responses (both innate and adaptive) are affected by glycan-mediated events. While the roles of glycans in norma ...

    STTR Department of Health and Human Services
  8. PA-16-157: New Technologies for the Glycosciences (R43/R44)

    Release Date: 03-30-2016Open Date: 08-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Carbohydrates (or glycans) play roles in a wide range of biological functions and disease processes. Nearly all aspects of biology, including: a) protein folding; b) cell adhesion and trafficking; c) cell signaling, fertilization and embryogenesis; and d) pathogen recognition and immune responses (both innate and adaptive) are affected by glycan-mediated events. While the roles of glycans in norma ...

    SBIR Department of Health and Human Services
  9. Strategies for the Improvement of HIV Envelope Protein Expression and Yield (R43/R44)

    Release Date: 04-12-2016Open Date: 08-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Purpose The purpose of this Funding Opportunity Announcement (FOA) is to encourage Small Business Innovation Research (SBIR) grant applications from Small Business Concerns (SBCs) and academic partners that will focus on innovative technologies and strategies to improve HIV envelope protein expression, yield and rapid universal purification platforms that would meet the requirements of regulatory ...

    SBIR Department of Health and Human Services
  10. Strategies for the Improvement of HIV Envelope Protein Expression and Yield (R41/R42)

    Release Date: 04-12-2016Open Date: 08-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Purpose The purpose of this Funding Opportunity Announcement (FOA) is to encourage Small Business Technology Transfer (STTR) grant applications from Small Business Concerns (SBCs) and non-profit research institutions that will focus on innovative technologies and strategies to improve HIV envelope protein expression, yield and rapid universal purification platforms that would meet the requirements ...

    STTR Department of Health and Human Services

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