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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. RFA-HD-18-102: Advancing the Science of Multipurpose Technology for the Prevention of HIV and Unintended Pregnancy (R43/R44)

    Release Date: 11-22-2017Open Date: 12-22-2017Due Date: 01-22-2018Close Date: 01-22-2018

    The purpose of this initiative is to invite SBIR applications to stimulate new and innovative multipurpose prevention technologies (MPTs) through the development of new combinations of agents and delivery systems to prevent HIV infection and unintended pregnancy among adolescent girls and young women.  HIV and unintended pregnancy are two major public health problems affecting young women glo ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  2. RFA-HD-18-101: Advancing the Science of Multipurpose Technology for the Prevention of HIV and Unintended Pregnancy (R41)

    Release Date: 11-22-2017Open Date: 12-22-2017Due Date: 01-22-2018Close Date: 01-22-2018

    Purpose The purpose of this initiative is to invite STTR applications to stimulate new and innovative multipurpose prevention technologies (MPTs) through the development of new combinations of agents and delivery systems to prevent HIV infection and unintended pregnancy among adolescent girls and young women.  HIV and unintended pregnancy are two major public health problems affecting young ...

    STTR Department of Health and Human ServicesNational Institutes of Health
  3. RFA-DK-17-029 : Support for Small Business Innovation Research to Develop New Open and Closed-Loop Automated Technologies for Better Type 1 Diabetes Therapy and Monitoring (SBIR) (R43/R44- Clinical Trial Not Allowed)

    Release Date: 12-21-2017Open Date: 02-21-2018Due Date: 03-21-2018Close Date: 03-21-2018

    Purpose and Research Objectives Despite the availability of increasingly effective treatment modalities, including insulin analogues, continuous glucose monitors (CGMs), and continuous subcutaneous insulin infusion (CSII) devices, a substantial proportion of patients with type 1 diabetes (T1D) cannot achieve adequate glycemic control and avoid acute complications such as hypoglycemia.  NID ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  4. RFA-DK-17-030 : Development of New Technologies and Bioengineering Solutions for the Advancement of Cell Replacement Therapies for Type 1 Diabetes (R43/R44 Clinical Trial Not Allowed)

    Release Date: 12-21-2017Open Date: 02-21-2018Due Date: 03-21-2018Close Date: 03-21-2018

    Purpose and Research Objectives Despite clear progress made during the last 15 years on cellular transplantation for T1D, the most recent results demonstrate a long term limited viability of engrafted islets and, as a result, limited insulin independence under different novel modalities of immunosuppressive (IS) regimens tested.  In addition, even the most innovative IS regimens required f ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  5. RFA-HD-19-006 : Non-invasive Diagnostics to Improve Gynecologic Health (R43/R44- Clinical Trial Optional)

    Release Date: 12-14-2017Open Date: 02-28-2018Due Date: 03-30-2018Close Date: 03-30-2018

    Purpose The purpose of the Non-invasive Diagnostics in Gynecologic Health RFA is to support SBIR projects to small businesses using advanced technologies (e.g., bio-chips, microfluidics, and mobile technologies) to develop novel or improved diagnostic approaches, tools, or devices for endometriosis, adenomyosis, and/or uterine fibroids. The ultimate goal of the program is to improve human gy ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  6. 001: NINDS Exploratory Clinical Trials for Small Business (R44)

    Release Date: 06-15-2015Open Date: 08-05-2015 Due Dates: Multiple Close Date: 04-05-2018

    Purpose The NINDS is committed to advancing treatments for people burdened by the neurological disorders that fall under the NINDS mission. Traditionally, large pharmaceutical and biotechnology companies, as well as venture capital firms, have provided the resources needed to conduct the clinical studies required to fully develop and commercialize biomedical products and technologies. More recentl ...

    SBIR Department of Health and Human Services
  7. 001: NINDS Exploratory Clinical Trials for Small Business (R42)

    Release Date: 06-15-2015Open Date: 08-05-2015 Due Dates: Multiple Close Date: 04-05-2018

    Purpose The NINDS is committed to advancing treatments for people burdened by the neurological disorders that fall under the NINDS mission.  Traditionally, large pharmaceutical and biotechnology companies, as well as venture capital firms, have provided the resources needed to conduct the clinical studies required to fully develop and commercialize biomedical products and technologies. More r ...

    STTR Department of Health and Human Services
  8. Small Market Awards: SBIR Phase IIB Competing Renewals for Heart, Lung, Blood, and Sleep Technologies with Small Commercial Markets (R44)

    Release Date: 04-18-2016Open Date: 05-20-2016 Due Dates: Multiple Close Date: 06-20-2018

    Purpose The Small Business Innovation Research (SBIR) Program is an important National Institutes of Health (NIH) funding mechanism used to develop innovative solutions that address public health challenges. A major objective of the SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of biomedical technology products ...

    SBIR Department of Health and Human Services
  9. 001: Novel Tools and Devices for Animal Research Facilities and to Support the Care of Animal Models (R43/R44)

    Release Date: 04-16-2015Open Date: 08-05-2015 Due Dates: Multiple Close Date: 09-05-2018

    Many NIH-funded research projects rely on vertebrate and invertebrate animals to study fundamentals of biology and physiology, to investigate pathological conditions, to build models of human diseases, and to design novel therapies and translational procedures. ORIP plays a vital role in the area of NIH-funded animal model research by supporting specialized animal research facilities and the devel ...

    SBIR Department of Health and Human Services
  10. 001: Development of Novel Tools and Devices to Support the Care of Animal Models and Animal Care Research Facilities (R41/R42)

    Release Date: 04-16-2015Open Date: 08-05-2015 Due Dates: Multiple Close Date: 09-05-2018

    Many NIH-funded research projects rely on vertebrate and invertebrate animals to study fundamentals of biology and physiology, to investigate pathological conditions, to build models of human diseases, and to design novel therapies and translational procedures. ORIP plays a vital role in the area of NIH-funded animal model research by supporting specialized animal research facilities and the devel ...

    STTR Department of Health and Human Services

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