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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. CBD18A-001: Circulating Diagnostic Markers of Infectious Disease

    Release Date: 11-29-2017Open Date: 01-08-2018Due Date: 02-07-2018Close Date: 02-07-2018

    TECHNOLOGY AREA(S): Chem Bio_defense, Bio Medical  OBJECTIVE: To provide increased diagnostic capability for diseases caused by biological threat agents. Capabilities sought are intended for use in clinics and forward deployed military medical treatment facilities and must be effective to diagnose disease with high clinical sensitivity within the first 10 days of symptom presentati ...

    STTR Office for Chemical and Biological DefenseDepartment of Defense
  2. CBD18A-002: Marburg Virus Prophylactic Medical Countermeasure

    Release Date: 11-29-2017Open Date: 01-08-2018Due Date: 02-07-2018Close Date: 02-07-2018

    TECHNOLOGY AREA(S): Chem Bio_defense, Bio Medical  OBJECTIVE: Develop a novel prophylactic medical countermeasure that will provide durable protection against Marburg virus exposure.  DESCRIPTION: Marburg virus is a filamentous enveloped non-segmented negative sense RNA virus and was first identified in 1967 during epidemics in Marburg and Frankfurt in Germany and Belgrad ...

    STTR Office for Chemical and Biological DefenseDepartment of Defense
  3. CBD181-002: Innovative Respiratory Protection for Low Threat Environments

    Release Date: 11-29-2017Open Date: 01-08-2018Due Date: 02-07-2018Close Date: 02-07-2018

    TECHNOLOGY AREA(S): Chem Bio_defense  OBJECTIVE: To develop a pressurized respiratory protection device for use in low threat environments without the use of rubber facial or neck seals.  DESCRIPTION: Current military respiratory protection systems such as the M50 are designed for a high threat environment. In part, the threat level requirements drive the utilization of r ...

    SBIR Office for Chemical and Biological DefenseDepartment of Defense
  4. CBD181-001: 3D Printed Manufacturing of Respiratory Protection

    Release Date: 11-29-2017Open Date: 01-08-2018Due Date: 02-07-2018Close Date: 02-07-2018

    TECHNOLOGY AREA(S): Chem Bio_defense, Materials  OBJECTIVE: Develop additive manufacturing processes to produce a fully functional Air Purifying Respirator (APR). Demonstrate advantages of 3D printed manufacturing to provide innovations such as custom sizing and use of multifunctional elastomeric composites.  DESCRIPTION: Many respiratory protection systems are designed ...

    SBIR Office for Chemical and Biological DefenseDepartment of Defense
  5. CBD181-004: Extended Release Formulations for Fielded Nerve Agent Pretreatment

    Release Date: 11-29-2017Open Date: 01-08-2018Due Date: 02-07-2018Close Date: 02-07-2018

    TECHNOLOGY AREA(S): Chem Bio_defense, Bio Medical  OBJECTIVE: Develop formulations of pyridostigmine bromide (PB) that afford pretreatment to nerve agent exposure by reducing the number of daily administrations of the fielded product, while maintaining a consistent reduction in blood acetylcholinesterase activity.  DESCRIPTION: Military operations occur under a wide-range ...

    SBIR Office for Chemical and Biological DefenseDepartment of Defense
  6. CBD181-005: Dual Formulation of Atropine/Scopolamine with Enhanced Stability

    Release Date: 11-29-2017Open Date: 01-08-2018Due Date: 02-07-2018Close Date: 02-07-2018

    TECHNOLOGY AREA(S): Chem Bio_defense, Bio Medical  OBJECTIVE: Develop stable, combined atropine/scopolamine formulations to exploit complementary pharmacological profiles for optimal muscarinic receptor blockade and anticholinergic activity within the peripheral and central nervous systems. The goal is to develop improved countermeasures against organophosphorus (OP) nerve agent ( ...

    SBIR Office for Chemical and Biological DefenseDepartment of Defense
  7. CBD181-006: Field Portable Mass Spectrometry for Small Molecule Drugs in Clinical Samples

    Release Date: 11-29-2017Open Date: 01-08-2018Due Date: 02-07-2018Close Date: 02-07-2018

    TECHNOLOGY AREA(S): Chem Bio_defense, Bio Medical  OBJECTIVE: To provide a rapid, easy to use method for human clinical sample testing that is effective for the detection and identification of novel designer drug combinations in non-traditional sample types. Capabilities sought should encompass the end-to-end method to include low invasive clinical sample collection and be suitabl ...

    SBIR Office for Chemical and Biological DefenseDepartment of Defense
  8. CBD181-007: Bi-specific Antibodies Targeting Disease Caused by Encephalitic Alphaviruses

    Release Date: 11-29-2017Open Date: 01-08-2018Due Date: 02-07-2018Close Date: 02-07-2018

    TECHNOLOGY AREA(S): Chem Bio_defense, Bio Medical  OBJECTIVE: The objective of this effort is to identify and develop bi-specific antibodies that demonstrate the capability to cross the blood brain barrier and neutralize encephalitic strains of Alphaviruses.  DESCRIPTION: There are no approved medical countermeasures that are available for the treatment of encephalitic al ...

    SBIR Office for Chemical and Biological DefenseDepartment of Defense
  9. CBD181-003: Durable Stretch Barrier Materials

    Release Date: 11-29-2017Open Date: 01-08-2018Due Date: 02-07-2018Close Date: 02-07-2018

    TECHNOLOGY AREA(S): Chem Bio_defense, Materials  OBJECTIVE: Commercially available Chemical, Biological, Radioactive, and Nuclear (CBRN) protective ensembles are bulky and with a high thermal burden due to the lack of stretch of the materials used. The bulk of the garment prevents agile movements of arms and legs needed while performing critical tasks. Materials with stretch enable ...

    SBIR Office for Chemical and Biological DefenseDepartment of Defense

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