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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. RFA-NS-22-033: Stroke Preclinical Assessment Network (SPAN) to Support Translational Studies for Acute Cerebroprotection- Interventions from Small Businesses (U44 Clinical Trial Not Allowed)

    Release Date: 01-06-2022Open Date: 02-14-2022Due Date: 03-14-2022Close Date: 03-15-2022

    Purpose The purpose of this funding opportunity announcement (FOA) is to solicit applications for cerebroprotective intervention research projects from eligible U.S. small businesses to be tested in the NINDS Stroke Preclinical Assessment Network (SPAN).SPAN will support late-stage preclinical studies of putative cerebroprotectants to be given prior to or at the time of reperfusion in rodent mode ...

    SBIRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. RFA-MD-22-004: Innovations for Healthy Living- Improving Minority Health and Eliminating Health Disparities (R43/R44- Clinical Trial Optional)

    Release Date: 01-05-2022Open Date: 03-05-2022Due Date: 04-04-2022Close Date: 04-05-2022

    Background Over the years, there has been continued improvement of health for Americans with the introduction of medical and scientific advances. Despite notable health improvements for the population as a whole through technological advancement, there continues to be an alarming disproportionate burden of illness among persons from racial and ethnic minority and other population groups who exper ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  3. RFA-MD-22-003: Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional)

    Release Date: 01-05-2022Open Date: 03-04-2022Due Date: 04-04-2022Close Date: 04-05-2022

    Background Over the years, there has been continued improvement of health for Americans with the introduction of medical and scientific advances. Despite notable health improvements for the population as a whole through technological advancement, there continues to be an alarming disproportionate burden of illness among persons from racial and ethnic minority and other population groups who exper ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  4. OSD22A-001: Multi-Scale Representation Learning

    Release Date: 12-01-2021Open Date: 01-12-2022Due Date: 02-10-2022Close Date: 02-10-2022

    OUSD (R&E) MODERNIZATION PRIORITY: Artificial intelligence/machine learning TECHNOLOGY AREA(S): Information systems, modeling and simulation technology OBJECTIVE: Develop a single neural network that learns representations at multiple spatial and semantic scales and that may be applied to different geospatial tasks, such as land cover segmentation, object detection, key-point matching, and ...

    STTRPhase I/Phase IIDepartment of DefenseNational Geospatial-Intelligence Agency
  5. OSD22A-002: Environmental Security Risk Forecasting

    Release Date: 12-01-2021Open Date: 01-12-2022Due Date: 02-10-2022Close Date: 02-10-2022

    OUSD (R&E) MODERNIZATION PRIORITY: Artificial intelligence/machine learning, statistical forecasting TECHNOLOGY AREA(S): Information systems, modeling and simulation technology OBJECTIVE: Develop computer models to forecast risk to US critical infrastructure from a range of potential climate futures. During Phase I, research will be restricted to modeling past and forecasting future wildfi ...

    STTRPhase I/Phase IIDepartment of DefenseNational Geospatial-Intelligence Agency
  6. OSD221-001: Scene Geometry Aided Automatic Target Recognition (ATR) for Radar

    Release Date: 12-01-2021Open Date: 01-12-2022Due Date: 02-10-2022Close Date: 02-10-2022

    OUSD (R&E) MODERNIZATION PRIORITY: Artificial intelligence/machine learning (AI/ML), autonomy TECHNOLOGY AREA(S): Information systems, sensors, electronics OBJECTIVE: Develop and demonstrate synthetic aperture radar (SAR) ATR that reduces false alarm rates by incorporating modern artificial intelligence and geometry of the imaged area. DESCRIPTION: The focus of this research incorporat ...

    SBIRPhase I/Phase IIDepartment of DefenseNational Geospatial-Intelligence Agency
  7. OSD221-002: Automatic Labeling of Multiple Target Synthetic Aperture Radar (SAR) Imagery for Automatic Target Recognition (ATR)

    Release Date: 12-01-2021Open Date: 01-12-2022Due Date: 02-10-2022Close Date: 02-10-2022

    OUSD (R&E) MODERNIZATION PRIORITY: Artificial intelligence/machine learning (AI/ML), autonomy TECHNOLOGY AREA(S): Information systems; sensors; electronics OBJECTIVE: Develop novel algorithms for labeling multiple target classes in Synthetic Aperture Radar (SAR) imagery to expedite training of SAR Automatic Target Recognition (ATR) algorithms. DESCRIPTION: The focus of this research wi ...

    SBIRPhase I/Phase IIDepartment of DefenseNational Geospatial-Intelligence Agency
  8. OSD221-003: Rapid Object Detector Development from Limited Labelled Data

    Release Date: 12-01-2021Open Date: 01-12-2022Due Date: 02-10-2022Close Date: 02-10-2022

    OUSD (R&E) MODERNIZATION PRIORITY: Artificial Intelligence / Machine Learning TECHNOLOGY AREA(S): Information Systems Technology- Modeling and Simulation Technology; Computing and Software Technology OBJECTIVE: Develop methods and science to rapidly produce object detectors for overhead imagery starting from a limited pool of hand-labeled data. DESCRIPTION: NGA utilizes deep learning d ...

    SBIRPhase I/Phase IIDepartment of DefenseNational Geospatial-Intelligence Agency
  9. OSD221-D04: High Resolution Near Real Time Land Use and Land Use Change

    Release Date: 12-01-2021Open Date: 01-12-2022Due Date: 02-10-2022Close Date: 02-10-2022

    OUSD (R&E) MODERNIZATION PRIORITY: Artificial intelligence/machine learning TECHNOLOGY AREA(S): Information systems, modeling and simulation technology OBJECTIVE: Develop a high-resolution fully automated land use and land use change (LULUC) map of the globe, updated daily, using commercial or publicly available satellite imagery. Identify mission-specific types of change in near real-time ...

    SBIRPhase I/Phase IIDepartment of DefenseNational Geospatial-Intelligence Agency
  10. RFA-HL-23-008: NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)

    Release Date: 11-16-2021Open Date: 01-28-2022 Due Dates: Multiple Close Date: 02-29-2024

    Since its inception in 1982, the NIH SBIR program has provided the small business community with seed funding to support the development of a broad array of commercial products to detect, diagnose, treat, and prevent disease.? It provides an important funding mechanism for bringing new interventions to patients and clinicians. The SBIR program is structured in three phases. The objective in Phase ...

    SBIRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
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