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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. NIH/NCATS 020: Development of Remote Rare Disease Patient Care Environment through Immersive Virtual Reality

    Release Date: 07-09-2020Open Date: 07-09-2020Due Date: 10-26-2020Close Date: 10-26-2020

    (Fast-Track proposals will not be accepted. Phase II information is provided only for informational purposes to assist Phase I offerors with their long-term strategic planning.) Number of anticipated awards: 1 to 3 Budget (total costs, per award): Phase I: $325,000 for 9-12 months; Phase II: $2,000,000 for 2 years It is strongly suggested that proposals adhere to the above budget amounts and pr ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. NIH/NCATS 021: Platform for Rapidly Deployable Autonomous Laboratory

    Release Date: 07-09-2020Open Date: 07-09-2020Due Date: 10-26-2020Close Date: 10-26-2020

    (Fast-Track proposals will not be accepted. Phase II information is provided only for informational purposes to assist Phase I offerors with their long-term strategic planning.) Number of anticipated awards: 1 to 3 Budget (total costs, per award): Phase I: $325,000 for 9 months; Phase II: $2,000,000 for 2 years It is strongly suggested that proposals adhere to the above budget amounts and proje ...

    SBIRPhase I/Phase IIDepartment of Health and Human Services
  3. NIH/NCI 413: Next Generation 3D Tissue Culture Systems with Tertiary Lymphoid Organs

    Release Date: 07-09-2020Open Date: 07-09-2020Due Date: 10-26-2020Close Date: 10-26-2020

    Fast-Track proposals will be accepted. Direct-to-Phase II proposals will NOT be accepted Number of anticipated awards: 3-5 Budget (total costs, per award): Phase I: up to $400,000 for up to 9 months Phase II: up to $2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary Tertiary lymphoid organs (TLOs) are lymph node-like structu ...

    SBIRPhase I/Phase IIDepartment of Health and Human Services
  4. NIH/NCI 414: Synthetic Biology Gene Circuits for Cancer Therapy

    Release Date: 07-09-2020Open Date: 07-09-2020Due Date: 10-26-2020Close Date: 10-26-2020

    Fast-Track proposals will NOT be accepted. Direct-to-Phase II proposals will be accepted Number of anticipated awards: 3 - 5 Budget (total costs, per award): Phase I: up to $400,000 for up to 9 months Phase II: up to $2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary Gene therapy has come of age over the past few years. One o ...

    SBIRPhase I/Phase IIDepartment of Health and Human Services
  5. NIH/NCI 415: Applicator-Compatible Electronic Brachytherapy Sources for Cancer Radiotherapy

    Release Date: 07-09-2020Open Date: 07-09-2020Due Date: 10-26-2020Close Date: 10-26-2020

    Fast-Track proposals will be accepted. Direct-to-Phase II proposals will NOT be accepted. Number of anticipated awards: 1-3 Budget (total costs, per award): Phase I: up to $400,000 for up to 9 months Phase II: up to $2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary This solicitation calls for the development of electronic devi ...

    SBIRPhase I/Phase IIDepartment of Health and Human Services
  6. NIH/NCI 416: Self-Sampling Devices for HPV-Testing-Based Cervical Cancer Screening

    Release Date: 07-09-2020Open Date: 07-09-2020Due Date: 10-26-2020Close Date: 10-26-2020

    Fast-Track proposals will be accepted. Direct-to-Phase II proposals will be accepted Number of anticipated awards: 3 - 5 Budget (total costs, per award): Phase I: up to $400,000 for up to 9 months Phase II: up to $2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary All currently recommended screening tests for cervical cancer req ...

    SBIRPhase I/Phase IIDepartment of Health and Human Services
  7. NIH/NCI 417: Quantitative Imaging Software Tools for Cancer Diagnosis and Treatment Planning

    Release Date: 07-09-2020Open Date: 07-09-2020Due Date: 10-26-2020Close Date: 10-26-2020

    Fast-Track proposals will be accepted. Direct-to-Phase II proposals will NOT be accepted Number of anticipated awards: 2-3 Budget (total costs, per award): Phase I: up to $400,000 for up to 9 months Phase II: up to $2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary Quantitative imaging software tools developed in academic set ...

    SBIRPhase I/Phase IIDepartment of Health and Human Services
  8. NIH/NCI 418: 3D Spatial Omics for Molecular and Cellular Tumor Atlas Construction

    Release Date: 07-09-2020Open Date: 07-09-2020Due Date: 10-26-2020Close Date: 10-26-2020

    Fast-Track proposals will be accepted. Direct-to-Phase II proposals will NOT be accepted Number of anticipated awards: 3-5 Budget (total costs, per award): Phase I: up to $400,000 for up to 9 months Phase II: up to $2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary Public large-scale molecular-level datasets have facilitated so ...

    SBIRPhase I/Phase IIDepartment of Health and Human Services
  9. NIH/NCI 419: Understanding Cancer Tumor Genomic Results: Technology Applications for Providers

    Release Date: 07-09-2020Open Date: 07-09-2020Due Date: 10-26-2020Close Date: 10-26-2020

    Fast-Track proposals will be accepted. Direct-to-Phase II proposals will NOT be accepted. Number of anticipated awards: 2-3 Budget (total costs, per award): Phase I: up to $400,000 for up to 9 months Phase II: up to $2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary Next-generation sequencing (NGS)–based technology has lowe ...

    SBIRPhase I/Phase IIDepartment of Health and Human Services
  10. NIH/NCI 420: Single-Cell “Unbiased Discovery” Proteomic Technologies

    Release Date: 07-09-2020Open Date: 07-09-2020Due Date: 10-26-2020Close Date: 10-26-2020

    Fast-Track proposals will NOT be accepted. Direct-to-Phase II proposals will NOT be accepted. Number of anticipated awards: 3-5 Budget (total costs, per award): Phase I: up to $400,000 for up to 9 months Phase II: up to $2,000,000 for up to 2 years PROPOSALS THAT EXCEED THE BUDGET OR PROJECT DURATION LISTED ABOVE MAY NOT BE FUNDED. Summary This proposal is for the development of high-throughput, s ...

    SBIRPhase I/Phase IIDepartment of Health and Human Services
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