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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. HHS-2021-ACL-NIDILRR-BISB-0026: Small Business Innovation Research Program (SBIR) Phase II Department of Health and Human Services Administration for Community Living

    Release Date: 03-30-2021Open Date: 03-30-2021Due Date: 06-01-2021Close Date: 06-01-2021

    SBIR Phase I grantees who successfully completed their Phase I grant in fiscal year 2019, 2020 or 2021 are eligible to apply. These eligible applicants only include (1) Phase I grantees who successfully completed their Phase I work within the past 3 years (2019, 2020, 2021) with Phase I funding from NIDILRR, or (2) Phase I grantees who successfully completed with Phase I work within the past 3 yea ...

    SBIRPhase IIDepartment of Health and Human ServicesAdministration for Community Living
  2. 8.12: Small and Mid-Size Farms

    Release Date: 12-28-2020Open Date: 12-28-2020Due Date: 05-03-2021Close Date: 05-03-2021

    The Small and Mid-Size Farms topic area aims to promote and improve the sustainability and profitability of small and mid-size farms and ranches (where annual sales of agricultural products are less than $250,000 for small farms and $500,000 for mid-size farms).

    SBIRPhase IIDepartment of AgricultureNational Institute of Food and Agriculture
  3. RFA-MH-21-112: Service-Ready Tools for Identification, Prevention, and Treatment of Individuals at Risk for Suicide (R43/R44 Clinical Trial Optional)

    Release Date: 11-13-2020Open Date: 01-18-2021 Due Dates: Multiple Close Date: 06-16-2022

    Research Strategy Applications should address the following additional issues: Rationale The rate of death by suicide in the United States has increased each year since 2005, from 11.0/100,000 to 14.8/100,000 of the population in 2018. Distinct subgroups have experienced even greater increases in the rate of suicide deaths during this period. With an estimated 20 suicide attempts per death by s ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  4. PAR-20-128: SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance (SB1, Clinical Trial Not Allowed)

    Release Date: 07-10-2020Open Date: 08-08-2020 Due Dates: Multiple Close Date: 04-06-2022

    Section I. Funding Opportunity Description Purpose The NIH Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs have provided the small business community with critical seed funding to support the development of a wide variety of technologies that benefit society. The main objective in SBIR/STTR Phase I is to establish the technical merit and feasibility ...

    SBIRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
  5. PAR-20-130: SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1 Clinical Trial Required)

    Release Date: 07-10-2020Open Date: 08-08-2020 Due Dates: Multiple Close Date: 04-06-2022

    Purpose The NIH Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs have provided the small business community with critical seed funding to support the development of a wide variety of technologies that benefit society. The main objective in SBIR/STTR Phase I is to establish the technical merit and feasibility of the proposed research and development ( ...

    SBIRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
  6. PAR-20-129: SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed)

    Release Date: 07-10-2020Open Date: 08-08-2020 Due Dates: Multiple Close Date: 04-06-2022

    Purpose The NIH Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs have provided the small business community with critical seed funding to support the development of a wide variety of technologies that benefit society. The main objective in SBIR/STTR Phase I is to establish the technical merit and feasibility of the proposed research and development ( ...

    SBIRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
  7. RFA-CA-21-036: SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)

    Release Date: 03-25-2021Open Date: 07-06-2021Due Date: 08-06-2021Close Date: 08-07-2021

    Purpose The Small Business Innovation Research (SBIR) Program is an important mechanism by which the National Institutes of Health (NIH) and other Federal agencies help bring innovative solutions to public health challenges. A major objective of the Federal SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of medi ...

    SBIRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
  8. 8.6: Rural and Community Development

    Release Date: 12-28-2020Open Date: 12-28-2020Due Date: 05-03-2021Close Date: 05-03-2021

    The Rural Development topic area aims to fund the development of new technology, or for the utilization of existing technology, that address important economic and social development issues or challenges in rural America. The applications need not be centered on agriculture but may be focused on any area that has the potential to provide significant benefit to rural Americans.

    SBIRPhase IIDepartment of AgricultureNational Institute of Food and Agriculture
  9. RFA-NS-20-011 : RFA-NS-20-011

    Release Date: 10-01-2019Open Date: 12-08-2019 Due Dates: Multiple Close Date: 09-08-2022

    Purpose The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Innovation Research (SBIR) program. Specifically, this FOA is focused on applications directed at improving pain measurement ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  10. 8.13: Plant Production and Protection- Engineering

    Release Date: 12-28-2020Open Date: 12-28-2020Due Date: 05-03-2021Close Date: 05-03-2021

    The objective of this topic area is to enhance crop production by creating and commercializing engineering technologies that enhance system efficiency and profitability and protect crops from pests and pathogens in economically and environmentally sound ways.

    SBIRPhase IIDepartment of AgricultureNational Institute of Food and Agriculture
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