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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. PAR-16-016: Novel Genomic Technology Development-(R43/R44)

    Release Date: 10-27-2015Open Date: 12-14-2015 Due Dates: Multiple Close Date: 01-11-2018

    Purpose This Funding Opportunity Announcement (FOA) seeks SBIR grant applications from small businesses to develop major advances in genomic technologies.  Advances in genomics and more broadly in biomedical research have been greatly facilitated by significant and sustained genomics technology throughput increases, cost decreases, and improvements in ease of use. The proposed technology deve ...

    SBIR Department of Health and Human Services
  2. Small Market Awards: SBIR Phase IIB Competing Renewals for Heart, Lung, Blood, and Sleep Technologies with Small Commercial Markets (R44)

    Release Date: 04-18-2016Open Date: 05-20-2016 Due Dates: Multiple Close Date: 06-20-2018

    Purpose The Small Business Innovation Research (SBIR) Program is an important National Institutes of Health (NIH) funding mechanism used to develop innovative solutions that address public health challenges. A major objective of the SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of biomedical technology products ...

    SBIR Department of Health and Human Services
  3. PAR-16-410: Wearable Alcohol Biosensors SBIR (R43/R44)

    Release Date: 08-17-2016Open Date: 11-06-2016 Due Dates: Multiple Close Date: 04-04-2019

    Rapid advances are being made in wearable technology, including clothing, jewelry and other devices with broadly diverse functions that meet medical or consumer needs.  This FOA seeks applications from small businesses that propose to design and produce a non-invasive wearable device to monitor blood alcohol levels in real time. Alcohol detection technology for personal alcohol monitoring has ...

    SBIR Department of Health and Human Services
  4. Small Business Alzheimer's Disease Research (R43/R44)

    Release Date: 02-01-2016Open Date: 03-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Alzheimer’s disease (AD) is the leading cause of dementia in those over the age of 65 and as many as 5 million Americans age 65 and older have AD.  As the population ages the number of people age 65 and older with AD is projected to increase between two and three fold by 2050 without a cure or prevention of the disease. AD is one of the most persistent and devastating dementing disorders of ...

    SBIR Department of Health and Human Services
  5. Small Business Alzheimer's Disease Research (R41/R42)

    Release Date: 02-01-2016Open Date: 03-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Alzheimer’s disease (AD) is the leading cause of dementia in those over the age of 65 and as many as 5 million Americans age 65 and older have AD.  As the population ages the number of people age 65 and older with AD is projected to increase between two and three fold by 2050 without a cure or prevention of the disease. AD is one of the most persistent and devastating dementing disorders of ...

    STTR Department of Health and Human Services
  6. PA-16-158 : New Technologies for the Glycosciences (R41/42)

    Release Date: 03-30-2016Open Date: 08-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Carbohydrates (or glycans) play roles in a wide range of biological functions and disease processes. Nearly all aspects of biology, including: a) protein folding; b) cell adhesion and trafficking; c) cell signaling, fertilization and embryogenesis; and d) pathogen recognition and immune responses (both innate and adaptive) are affected by glycan-mediated events. While the roles of glycans in norma ...

    STTR Department of Health and Human Services
  7. PA-16-157: New Technologies for the Glycosciences (R43/R44)

    Release Date: 03-30-2016Open Date: 08-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Carbohydrates (or glycans) play roles in a wide range of biological functions and disease processes. Nearly all aspects of biology, including: a) protein folding; b) cell adhesion and trafficking; c) cell signaling, fertilization and embryogenesis; and d) pathogen recognition and immune responses (both innate and adaptive) are affected by glycan-mediated events. While the roles of glycans in norma ...

    SBIR Department of Health and Human Services
  8. Strategies for the Improvement of HIV Envelope Protein Expression and Yield (R43/R44)

    Release Date: 04-12-2016Open Date: 08-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Purpose The purpose of this Funding Opportunity Announcement (FOA) is to encourage Small Business Innovation Research (SBIR) grant applications from Small Business Concerns (SBCs) and academic partners that will focus on innovative technologies and strategies to improve HIV envelope protein expression, yield and rapid universal purification platforms that would meet the requirements of regulatory ...

    SBIR Department of Health and Human Services
  9. Strategies for the Improvement of HIV Envelope Protein Expression and Yield (R41/R42)

    Release Date: 04-12-2016Open Date: 08-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Purpose The purpose of this Funding Opportunity Announcement (FOA) is to encourage Small Business Technology Transfer (STTR) grant applications from Small Business Concerns (SBCs) and non-profit research institutions that will focus on innovative technologies and strategies to improve HIV envelope protein expression, yield and rapid universal purification platforms that would meet the requirements ...

    STTR Department of Health and Human Services
  10. Products to Support Applied Research Towards Zero Suicide Healthcare Systems (R43/R44)

    Release Date: 04-12-2016Open Date: 08-05-2016 Due Dates: Multiple Close Date: 04-05-2019

    Research Objectives This FOA supports the development of health IT products to advance the “Zero Suicide” goal of preventing suicide attempts and deaths among individuals under care within health systems.  A significant proportion of U.S. suicide decedents (more than 40,000 annually) have accessed health care within the year of their death, with estimates ranging from 30% to 80%, mirrorin ...

    SBIR Department of Health and Human Services

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