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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. DE-FOA-0002239: Aviation-Class Synergistically Cooled ElectricMotors with Integrated Drives (ASCEND)

    Release Date: 12-16-2019Open Date: 12-16-2019Due Date: 01-31-2020Close Date: 01-31-2020

    The ASCEND program supports the development of novel lightweight and ultra-efficient electric motors, drives, and associated thermal management system (collectively referred to as the all-electric powertrain) that will facilitate net-zero carbon emissions in the single-aisle, 150-200 passenger commercial aircraft segment. This FOA represents part of a wider ARPA-E effort in the development of enab ...

    SBIR/STTRPhase I/Phase IIDepartment of EnergyARPA-E
  2. DE-FOA-0002241: Range Extenders for Electric Aviation with Low Carbon and High Efficiency (REEACH)

    Release Date: 12-16-2019Open Date: 12-16-2019Due Date: 01-31-2020Close Date: 01-31-2020

    ARPA-E seeks to mitigate the greenhouse gas emissions associated with commercial air travel at minimum economic cost by developing elements of an ultra-high efficient aircraft propulsion system that uses Carbon Neutral Liquid Fuels (CNLFs). Since these fuels generally either have lower specific-energies (kWh/kg) or are projected to have higher cost than traditional fossil-based jet fuels, ultra-hi ...

    SBIR/STTRPhase I/Phase IIDepartment of EnergyARPA-E
  3. DE-FOA-0002251: Systems for Monitoring and Analytics for Renewable Transportation Fuels from Agricultural Resources and Management (SMARTFARM)

    Release Date: 12-18-2019Open Date: 12-18-2019Due Date: 02-19-2020Close Date: 02-19-2020

    U.S. agriculture has the potential to produce ~5 Quadrillion Btu of energy in the form of biofuels, and with new innovations throughout the biofuel supply chain, these fuels could become carbon negative. Reaching this potential and achieving greater carbon reductions requires that feedstock producers adopt new technologies and management practices that simultaneously improve yield, drive down prod ...

    SBIR/STTRPhase I/Phase IIDepartment of EnergyARPA-E
  4. PA-19-272: PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)

    Release Date: 05-07-2019Open Date: 08-05-2019 Due Dates: Multiple Close Date: 04-06-2020

    The SBIR program, as established by law, is intended to meet the following goals: stimulate technological innovation in the private sector; strengthen the role of small business in meeting Federal research or research and development (R/R&D) needs; increase the commercial application of Federally-supported research results; foster and encourage participation by socially and economically disadvanta ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  5. PA-19-273: PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)

    Release Date: 05-07-2019Open Date: 08-05-2019 Due Dates: Multiple Close Date: 04-06-2020

    The SBIR program, as established by law, is intended to meet the following goals: stimulate technological innovation in the private sector; strengthen the role of small business in meeting Federal research or research and development (R/R&D) needs; increase the commercial application of Federally-supported research results; foster and encourage participation by socially and economically disadvanta ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  6. PA-19-270: PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed

    Release Date: 05-07-2019Open Date: 08-05-2019 Due Dates: Multiple Close Date: 04-06-2020

    The STTR program, as established by law, is intended to stimulate a partnership of ideas and technologies between innovative small business concerns (SBCs) and non-profit research institutions through Federally-funded research or research and development (R/R&D). By providing awards to SBCs for cooperative R/R&D efforts with non-profit research institutions, the STTR program assists the small busi ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  7. PA-19-271: PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required

    Release Date: 05-07-2019Open Date: 08-05-2019 Due Dates: Multiple Close Date: 04-07-2020

    The STTR program, as established by law, is intended to stimulate a partnership of ideas and technologies between innovative small business concerns (SBCs) and non-profit research institutions through Federally-funded research or research and development (R/R&D). By providing awards to SBCs for cooperative R/R&D efforts with non-profit research institutions, the STTR program assists the small busi ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  8. RFA-NS-19-017 : HEAL Initiative: Translational Devices to Treat Pain (U44 Clinical Trial Optional)

    Release Date: 12-10-2018Open Date: 12-10-2018 Due Dates: Multiple Close Date: 02-22-2021

    Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to encourage small business concerns (SBCs) to pursue translational activities and clinical trials to treat pain with innovative, targeted, and non-addictive diagnostic and/or therapeutic devices that improve patient outcomes and decrease or eliminate the need to prescribe opioids. Activities supported in this program include ...

    SBIRPhase IIDepartment of Health and Human Services
  9. PAR-19-266 : Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R41/R42 Clinical Trial Not Allowed)

    Release Date: 05-02-2019Open Date: 08-05-2019 Due Dates: Multiple Close Date: 04-05-2021

    Many NIH-funded research projects rely on vertebrate and invertebrate animals to study basics of biology and physiology, to investigate pathological conditions, to build models of human diseases, and to design novel therapies and translational procedures. ORIP plays a vital role in the area of NIH-funded animal model research by supporting specialized animal research facilities and the development ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  10. PAR-19-265 : Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed)

    Release Date: 05-02-2019Open Date: 08-05-2019 Due Dates: Multiple Close Date: 04-05-2021

    Many NIH-funded research projects rely on vertebrate and invertebrate animals to study basics of biology and physiology, to investigate pathological conditions, to build models of human disease pathways, and to design novel therapies and translational procedures. ORIP plays a vital role in the area of NIH-funded animal model research by supporting specialized animal research facilities and the dev ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health

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