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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. L: Insulating Nanofluids and Solids to Upgrade our Large Aging Transformer Equipment (INSULATE)

    Release Date: 05-20-2020Open Date: 05-20-2020Due Date: 07-22-2020Close Date: 07-22-2020

    ARPA-E is interested in receiving Full Applications in support of exploring vital insulating elements in large power transformers (LPTs) in order to increase their resilience. In particular, the objective of this topic is to explore solutions related to increasing the life expectancy of the transformer, including: (i) high-performance solid insulation materials, (ii) advanced insulating fluids wit ...

    SBIR/STTRPhase I/Phase IIDepartment of EnergyARPA-E
  2. M: Mining Incinerated Disposal Ash Streams (MIDAS)

    Release Date: 05-20-2020Open Date: 05-20-2020Due Date: 07-22-2020Close Date: 07-22-2020

    ARPA-E is interested in receiving Full Applications in support of advancing the recovery and reclamation of CMs and other valuable elements from MSWI ashes. The broad objective of the MIDAS topic is to explore (i) real-time, cost-effective elemental identification techniques for MSWI ash, (ii) economically feasible methods of concentrating and extracting elements that may initially be in low conce ...

    SBIR/STTRPhase I/Phase IIDepartment of EnergyARPA-E
  3. N: Waste Into X (WIX)

    Release Date: 05-20-2020Open Date: 05-20-2020Due Date: 07-22-2020Close Date: 07-22-2020

    ARPA-E is interested in receiving Full Applications in support of advancing the beneficiation of MSWI ash into valuable products. The broad objective of the WiX topic is to explore (i) real-time, cost-effective characterization techniques for the MSWI ash output stream, (ii) the feasibility of adding co-feeds to waste pre-combustion, or to the MSWI ash post-combustion to yield a consistent product ...

    SBIR/STTRPhase I/Phase IIDepartment of EnergyARPA-E
  4. O: Direct Removal of Carbon Dioxide from Oceanwater (DOC)

    Release Date: 05-20-2020Open Date: 05-20-2020Due Date: 07-22-2020Close Date: 07-22-2020

    Capture of dispersed greenhouse gases (GHGs) is an important part of a diversified portfolio of technologies to mitigate U.S. GHG emissions. A large portion of the 5.2 gigatons (Gt) of CO2 emitted each year in the United States is released in relatively small quantities from distributed sources (e.g., from small point sources or some transportation sources). For such emissions, point source captur ...

    SBIR/STTRPhase I/Phase IIDepartment of EnergyARPA-E
  5. P: Direct Removal of Carbon Dioxide from Ambient Air (DAC)

    Release Date: 05-20-2020Open Date: 05-20-2020Due Date: 07-22-2020Close Date: 07-22-2020

    Capture of dispersed greenhouse gases (GHGs) is an important part of a diversified portfolio of technologies to mitigate U.S. GHG emissions. A large portion of the 5.2 gigatons (Gt) of CO2 emitted each year in the United States is released in relatively small quantities from distributed sources (e.g., from small point sources or some transportation sources). For such emissions, point source captur ...

    SBIR/STTRPhase I/Phase IIDepartment of EnergyARPA-E
  6. RFA-HD-21-007: Development of Fertility Regulation Methods by Small Business (R43/R44 Clinical Trial Optional)

    Release Date: 04-10-2020Open Date: 06-30-2020Due Date: 07-30-2020Close Date: 07-31-2020

    Purpose The purpose of this FOA is to invite SBIR applications to support and facilitate the development of new and/or improved non-hormonal contraceptive, including contraceptives with anti-infective properties, products for men and women. Background Nearly half of all pregnancies in the United States are unintended. There is a critical need for fertility regulation methods, including those th ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  7. RFA-CA-20-033 : SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)

    Release Date: 03-06-2020Open Date: 07-03-2020Due Date: 08-03-2020Close Date: 08-03-2020

    Purpose The Small Business Innovation Research (SBIR) Program is an important mechanism by which the National Institutes of Health (NIH) and other Federal agencies help bring innovative solutions to public health challenges. A major objective of the Federal SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of medi ...

    SBIRPhase IIDepartment of Health and Human ServicesNational Institutes of Health
  8. PAR-17-457 : CREATE Bio Optimization Track for Biologics (SBIR-U44)

    Release Date: 08-14-2017Open Date: 01-13-2018 Due Dates: Multiple Close Date: 09-07-2020

    A. Overview This Funding Opportunity Announcement (FOA) is part of a suite of complementary programs to encourage the translation of research discoveries into new treatments for disorders that fall under the NINDS mission. The NINDS Cooperative Research to Enable and Advance Translational Enterprises for Biologics (CREATE Bio) program is dedicated to biotechnology product- and biologics-based th ...

    SBIRPhase IIDepartment of Health and Human Services
  9. PAR-18-543 : CREATE Bio Development Track: Nonclinical and Early-Phase Clinical Development for Biologics (U44 Clinical Trial Optional)

    Release Date: 12-20-2017Open Date: 01-20-2018 Due Dates: Multiple Close Date: 09-07-2020

    A. Overview This Funding Opportunity Announcement (FOA) is part of a suite of complementary programs to encourage the translation of research discoveries into new treatments for disorders that fall under the NINDS mission. The NINDS Cooperative Research to Enable and Advance Translational Enterprises for Biologics (CREATE Bio) program is dedicated to biotechnology products and biologics-bas ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  10. PAR-18-549 : Analytical Validation of a Candidate Biomarker for Neurological Disease (U44 Clinical Trial Optional)

    Release Date: 12-22-2017Open Date: 02-14-2018 Due Dates: Multiple Close Date: 09-07-2020

    Purpose The overarching purpose of this Funding Opportunity Announcement (FOA) is to fill critical scientific gaps needed to advance strong candidate biomarkers of neurological disease from discovery to clinical use. Specifically, the focus of this FOA is on the validation of analytical methods for biomarker measurements, including evaluation of the assay, its performance characteristics, and t ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health

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