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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. NIH/NIAID 134: Alternatives to Benzathine Penicillin for Treatment of Syphilis

    Release Date: 08-25-2023Open Date: 08-25-2023Due Date: 11-14-2023Close Date: 11-14-2023

    Fast-Track proposals will be accepted Direct-to-Phase II proposals will be accepted Number of anticipated awards: 2-3 Budget (total costs): Phase I: $300,000 for up to one year; Phase II: $1,500,000 for up to 3 years Background Injectable benzathine penicillin (BPG) is currently the only CDC-recommended first line therapy for treatment of infection with Treponema pallidum (syphilis) in all populat ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. SOCOM234-001: Analyzing Narrative Evolution Across Social Networks

    Release Date: 11-15-2022Open Date: 11-15-2022Due Date: 12-31-2023Close Date: 12-31-2023

    The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), which controls the export and import of defense-related material and services. Offerors must disclose any proposed use of foreign nationals, their country of origin, and what tasks each would accomplish in the statement of work in accordance with section 5.4.c.(8) of the solicitation. Addition ...

    SBIRPhase I/Phase IIDepartment of DefenseSpecial Operations Command
  3. DHA234-D001: Anti-Shock Drug, Pre-Hospital (ASD-PH)

    Release Date: 11-15-2022Open Date: 11-15-2022Due Date: 12-31-2023Close Date: 12-31-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Combat Casualty Care OBJECTIVE: Develop a drug that would be useful in a pre-hospital setting for treatment of hemorrhagic shock in humans. DESCRIPTION: Severe blood loss, such as may be experienced in combat or other settings, if left untreated, will result in a deficiency of oxygen that will lead to the death of cells, tissues, and organs, and ultimately ...

    SBIRPhase I/Phase IIDepartment of DefenseDefense Health Agency
  4. DMEA23C-P001: Applications to Assist in Analysis and Re-Engineering of Printed Circuit Board Assemblies

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Microelectronics OBJECTIVE: Design and implement technologies to assist in the process of extracting a printed circuit board design non-destructively from a printed circuit board assembly. These technologies may be purely software based or include a hardware component. DESCRIPTION: The weapons systems of the Department of Defense (DoD) rely heavily on mic ...

    STTRPhase IDepartment of DefenseDefense Microelectronics Activity
  5. AF233-D008: AR for Equipment Maintenance

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Human-Machine Interfaces The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regulation (EAR), 15 CFR Parts 730-774, which con ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
  6. A234-008: Army Tech Marketplace

    Release Date: 11-15-2022Open Date: 11-15-2022Due Date: 12-31-2023Close Date: 12-31-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Advanced Computing and Software, Integrated Network Systems-of-Systems and Trusted AI and Autonomy TOPIC OBJECTIVE: To develop, integrate and deploy a technology with a simple intuitive user interface to improve information exchange and the discovery of collaboration opportunities within the Army R&D and Acquisitions communities as well as between the Army ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  7. N233-118: Artificial Intelligence (AI) and Autonomy for Improved Operations and Modernization of Navy Shipyards

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Human-Machine Interfaces;Sustainment;Trusted AI and Autonomy OBJECTIVE: Modernize Navy Shipyard facilities through three lines of effort: Drydocks, Infrastructure, and Industrial Plant Equipment. Digital technology to include digital twins, AI, and autonomy will bring these century old shipyards up to modern practices. Upgrading and modernizing shipyard ope ...

    SBIRPhase I/Phase IIDepartment of DefenseNavy
  8. A234-007: Artificial Intelligence (AI)/ Machine Learning (ML) Open Topic

    Release Date: 11-15-2022Open Date: 11-15-2022Due Date: 12-31-2023Close Date: 12-31-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Trusted AI and Autonomy TOPIC OBJECTIVE: The purpose of an Artificial Intelligence (AI)/ Machine Learning (ML) focused Open Topic is to bring potentially valuable small business innovations to the Army and create an opportunity to expand the relevance of the Army SBIR program to firms who do not normally compete for SBIR awards. TOPIC DESCRIPTION: This op ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  9. HR0011SB20234-10: Assessing Virtual Private Network (VPN) Networthiness (AVN)

    Release Date: 11-15-2022Open Date: 11-15-2022Due Date: 12-31-2023Close Date: 12-31-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Integrated Sensing and Cyber, Advanced computing and Software OBJECTIVE: The Assessing Virtual Private Network (VPN) Networthiness (AVN) SBIR topic seeks to develop and demonstrate techniques and systems for automatically analyzing third-party commercial VPN solutions to determine the actual operational privacy profile/performance of such services. DESCRIP ...

    SBIRPhase I/Phase IIDepartment of DefenseDefense Advanced Research Projects Agency
  10. AF233-D022: Austere Cargo Offload and Onload System

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Trusted AI and Autonomy;Advanced Computing and Software The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regulation (EAR), ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
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