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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. RFA-TR-22-032: Botulinum Toxin Potency Assay using Tissue Chips (BoT PATCh) (U43/U44- Clinical Trail Not Allowed)

    Release Date: 09-19-2022Open Date: 10-21-2022 Due Dates: Multiple Close Date: 08-22-2023

    Section I. Funding Opportunity Description This Funding Opportunity Announcement (FOA) invites eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR)Phase I and Phase II (Fast track and Direct to phase II) grant applications. The funding opportunity will utilize a U43/U44 cooperative agreement to support small business concerns (SBCs) to propose a ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. HHS-2023-ACL-NIDILRR-BISA-0000: Small Business Innovation Research (SBIR) program, Phase I

    Release Date: 10-17-2022Open Date: 10-17-2022Due Date: 12-16-2022Close Date: 12-16-2022

    NIDILRR¡¦s mission is to generate new knowledge and to promote its effective use to improve the abilities of individuals with disabilities to perform activities of their choice in the community and to expand society¡¦s capacity to provide full opportunities and accommodations for its citizens with disabilities. All SBIR projects funded by NIDILRR must address the needs of individuals with disa ...

    SBIRPhase IDepartment of Health and Human ServicesAdministration for Community Living
  3. C55-01: ACCELERATING THE DEPLOYMENT OF ADVANCED SOFTWARE TECHNOLOGIES

    Release Date: 09-29-2022Open Date: 09-29-2022Due Date: 12-31-2022Close Date: 12-31-2022

    Deployment of ASCR-Funded Software Integration of ASCR-Funded Libraries Other C55-01 FY2023 Phase I Release 1 Department of Energy ...

    SBIR/STTRPhase IDepartment of Energy
  4. C55-02: HPC CYBERSECURITY

    Release Date: 09-29-2022Open Date: 09-29-2022Due Date: 12-31-2022Close Date: 12-31-2022

    Cybersecurity Technologies Other C55-02 FY2023 Phase I Release 1 Department of Energy ...

    SBIR/STTRPhase IDepartment of Energy
  5. C55-03: DIGITAL TWIN CAPABILITIES FOR SCIENCE NETWORK INFRASTRUCTURES

    Release Date: 09-29-2022Open Date: 09-29-2022Due Date: 12-31-2022Close Date: 12-31-2022

    Network Simulation Tools Other C55-03 FY2023 Phase I Release 1 Department of Energy ...

    SBIR/STTRPhase IDepartment of Energy
  6. C55-04: TECHNOLOGY TO FACILITATE THE USE OF NEAR-TERM QUANTUM COMPUTING HARDWARE

    Release Date: 09-29-2022Open Date: 09-29-2022Due Date: 12-31-2022Close Date: 12-31-2022

    Software for Calibration, Characterization, and Control of Quantum Processors Ultra-Low-Loss Integration of Heterogeneous Quantum Internet Devices C55-04 FY2023 Phase I Release 1 Department of Energy ...

    SBIR/STTRPhase IDepartment of Energy
  7. C55-05: DEVELOPMENT OF TOOLS FOR INTEGRATING AND UTILIZING COMPLEX DATA FROM CHEMICAL SCIENCES, GEOSCIENCES, AND BIOSCIENCES

    Release Date: 09-29-2022Open Date: 09-29-2022Due Date: 12-31-2022Close Date: 12-31-2022

    AI/ML Framework for Multi-Modal Analysis of Complex Data Other C55-05 FY2023 Phase I Release 1 Department of Energy ...

    SBIR/STTRPhase IDepartment of Energy
  8. C55-06: CRYOSTAT FOR TESTING SUPERCONDUCTING UNDULATOR MAGNETS

    Release Date: 09-29-2022Open Date: 09-29-2022Due Date: 12-31-2022Close Date: 12-31-2022

    Development of Cryostat for Testing Superconducting Undulator Magnets Other C55-06 FY2023 Phase I Release 1 Department of Energy ...

    SBIR/STTRPhase IDepartment of Energy
  9. C55-07: NOVEL INSTRUMENTS AND TECHNIQUES FOR DETECTION AND REMOVAL OF CONTAMINATION PARTICULATES IN HIGH-POWER PROTON SUPERCONDUCTING LINAC RADIO FREQUENCY CAVITIES

    Release Date: 09-29-2022Open Date: 09-29-2022Due Date: 12-31-2022Close Date: 12-31-2022

    Non-Invasive Instruments for Detecting Particulate Movement in SRF Linac Beamlines and Tools and Processes for In-Situ Removal of Particulates from SRF Cavity Surfaces of a Cryomodule without Taking Apart Cryomodule Components Other C55-07 FY2023 Phase I ...

    SBIR/STTRPhase IDepartment of Energy
  10. C55-08: HIGH REPETITION RATE SAMPLE DELIVERY SYSTEM FOR SUPERCONDUCTING-RF AND MULTI-BUNCH X-RAY FREE ELECTRON LASER

    Release Date: 09-29-2022Open Date: 09-29-2022Due Date: 12-31-2022Close Date: 12-31-2022

    Development of High-Variable Speed Rotating Disks with Vibration Control and Long Lifetime Other C55-08 FY2023 Phase I Release 1 Department of Energy ...

    SBIR/STTRPhase IDepartment of Energy
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