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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. OSD233-004: Advanced Single-Photon Avalanche Diode for 1030 nm (SPAD-1030)

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Space Technology OBJECTIVE: Develop a single-photon avalanche detector for mm-accurate multi-kHz satellite and lunar laser ranging at 1030 nm. DESCRIPTION: High-accuracy satellite and lunar laser ranging (SLR/LLR) stations have heavily relied upon the availability of short pulse, frequency-doubled Nd:YAG and Yb:YAG lasers. This has driven SLR/LLR rec ...

    SBIRPhase I/Phase IIDepartment of DefenseNational Geospatial-Intelligence Agency
  2. PAS-22-196: Advancing Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional)

    Release Date: 06-21-2022Open Date: 12-05-2022 Due Dates: Multiple Close Date: 09-08-2025

    Recommendations and milestones for Alzheimer's disease (AD) and AD-related dementias (ADRD) research from the National Alzheimer’s Project Act and the 2015, 2018, 2019, and 2021 Alzheimer's Disease Research Summits present a wide range of research and development proposals which, if pursued, have the potential to reduce the human burden and healthcare costs associated with AD/ADRD. As part of t ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  3. PAS-22-197: Advancing Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional)

    Release Date: 06-21-2022Open Date: 12-05-2022 Due Dates: Multiple Close Date: 09-06-2025

    Recommendations and milestones for Alzheimer's disease (AD) and AD-related dementias (ADRD) research from the National Alzheimer’s Project Act and, the 2015, 2018, 2019, and 2021 Alzheimer's Disease Research Summits present a wide range of research and development proposals which, if pursued, have the potential to reduce the human burden and healthcare costs associated with AD/ADRD. As part of ...

    STTRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  4. A234-001 : AI/ML for Nitramine Recrystallization and Coating

    Release Date: 11-15-2022Open Date: 11-15-2022Due Date: 12-31-2023Close Date: 12-31-2023

    OUSD (R&E) MODERNIZATION PRIORITY: Artificial Intelligence/Machine Learning TECHNOLOGY AREA(S): Information Systems TOPIC OBJECTIVE:  To develop a suite of probe technology and machine learning algorithms which can be used throughout the energetics manufacturing process to reduce cost and increase product consistency. TOPIC DESCRIPTION:  Currently, nitramine energetic materials have unaccep ...

    SBIRPhase I/Phase IIDepartment of DefenseArmy
  5. AI1: AI-optimized Hardware

    Release Date: 11-22-2022Open Date: 11-22-2022 Due Dates: Multiple Close Date: 11-01-2023

    NA

    SBIR/STTRPhase INational Science Foundation
  6. SF233-D006: Aircraft avoidance for small telescopes using passive detection

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Directed Energy (DE);Space Technology The technology within this topic is restricted under the International Traffic in Arms Regulation (ITAR), 22 CFR Parts 120-130, which controls the export and import of defense-related material and services, including export of sensitive technical data, or the Export Administration Regulation (EAR), 15 CFR Parts 730-774, ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
  7. AF233-D002: Aircraft Vibration Harvester (AVH)

    Release Date: 08-23-2023Open Date: 09-20-2023Due Date: 10-18-2023Close Date: 10-18-2023

    OUSD (R&E) CRITICAL TECHNOLOGY AREA(S): Advanced Computing and Software;Integrated Sensing and Cyber OBJECTIVE: Develop and manufacture an energy harvesting system to be used in airborne applications. DESCRIPTION: Current solutions for installing instrumentation systems on flight-test aircrafts are time consuming, consist of large amounts of cabling, and require extensive aircraft downtime ...

    SBIRPhase I/Phase IIDepartment of DefenseAir Force
  8. CH1: Algorithms and Applications

    Release Date: 11-22-2022Open Date: 11-22-2022 Due Dates: Multiple Close Date: 11-01-2023

    NA

    SBIR/STTRPhase INational Science Foundation
  9. NIH/NIAID 134: Alternatives to Benzathine Penicillin for Treatment of Syphilis

    Release Date: 08-25-2023Open Date: 08-25-2023Due Date: 11-14-2023Close Date: 11-14-2023

    Fast-Track proposals will be accepted Direct-to-Phase II proposals will be accepted Number of anticipated awards: 2-3 Budget (total costs): Phase I: $300,000 for up to one year; Phase II: $1,500,000 for up to 3 years Background Injectable benzathine penicillin (BPG) is currently the only CDC-recommended first line therapy for treatment of infection with Treponema pallidum (syphilis) in all populat ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  10. HC1: Analytics

    Release Date: 11-22-2022Open Date: 11-22-2022 Due Dates: Multiple Close Date: 11-01-2023

    NA

    SBIR/STTRPhase INational Science Foundation
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