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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.

If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. PA-15-065: HHS SBIR PA-15-065

    Release Date: 12-10-2014Open Date: 03-06-2015 Due Dates: Multiple Close Date: 01-07-2018

    Purpose The purpose of this Funding Opportunity Announcement (FOA) is to encourage Small Business Innovation Research (SBIR) grant applications (Phase I [R43] and Phase II [R44]) focused on specific product development activities for radiological/nuclear medical countermeasures leading to Investigational New Drug (IND) or Investigational Device Exemption (IDE) submission packages to the U.S. Foo ...

    SBIR Department of Health and Human Services
  2. PA-15-077: HHS SBIR PA-15-077

    Release Date: 12-18-2014Open Date: 03-05-2015 Due Dates: Multiple Close Date: 01-07-2018

    Despite advances in the treatment of chronic viral hepatitis B and C, the persistence of these and the emergence of other hepatitis viruses continue to remain a public health challenge in the United States. Currently, it is estimated that 3.5 to 5.3 million persons in the United States are afflicted by viral hepatitis. The consequences of acute and chronic viral hepatitis vary, but can be severe a ...

    SBIR Department of Health and Human Services
  3. PA-15-076: HHS STTR PA-15-076

    Release Date: 12-18-2014Open Date: 03-05-2015 Due Dates: Multiple Close Date: 01-07-2018

    Despite advances in the treatment of chronic viral hepatitis B and C, the persistence of these and the emergence of other hepatitis viruses continue to remain a public health challenge in the United States. Currently, it is estimated that 3.5 to 5.3 million persons in the United States are afflicted by viral hepatitis. The consequences of acute and chronic viral hepatitis vary, but can be severe a ...

    STTR Department of Health and Human Services
  4. PA-15-086: HHS SBIR PA-15-086

    Release Date: 01-12-2015Open Date: 03-05-2015 Due Dates: Multiple Close Date: 01-07-2018

    The zebrafish is used extensively by NIH funded investigators to examine many aspects of the basic biology of vertebrates and, in the past several years, has become an important model organism for a variety of human diseases. During fiscal year 2013, twenty of the NIH Institutes, Centers and Offices funded approximately 700 grants related to zebrafish research, with an investment totaling approxim ...

    SBIR Department of Health and Human Services
  5. PA-15-087: HHS STTR PA-15-087

    Release Date: 01-12-2015Open Date: 03-05-2015 Due Dates: Multiple Close Date: 01-07-2018

    The zebrafish is used extensively by NIH funded investigators to examine many aspects of the basic biology of vertebrates and, in the past several years, has become an important model organism for a variety of human diseases. During fiscal year 2013, twenty of the NIH Institutes, Centers and Offices funded approximately 700 grants related to zebrafish research, with an investment totaling approxim ...

    STTR Department of Health and Human Services
  6. PAR-16-016: Novel Genomic Technology Development-(R43/R44)

    Release Date: 10-27-2015Open Date: 12-14-2015 Due Dates: Multiple Close Date: 01-11-2018

    Purpose This Funding Opportunity Announcement (FOA) seeks SBIR grant applications from small businesses to develop major advances in genomic technologies.  Advances in genomics and more broadly in biomedical research have been greatly facilitated by significant and sustained genomics technology throughput increases, cost decreases, and improvements in ease of use. The proposed technology deve ...

    SBIR Department of Health and Human Services
  7. RFA-ES-17-008 : Organotypic Culture Models developed from Experimental Animals for Chemical Toxicity Screening (R43/R44)

    Release Date: 09-05-2017Open Date: 12-12-2017Due Date: 01-12-2018Close Date: 01-12-2018

    Purpose This FOA solicits Phase I (R43) or Fast-track (R44) SBIR grant applications from SBCs to develop novel, engineered 3-dimensional or organotypic in vitro systems using cells from experimental animal models typically used for toxicology testing (e.g., rat, mouse, rabbit, or dog) that will replicate biological responses within the corresponding animal tissues or organs and can provide altern ...

    SBIR Department of Health and Human ServicesNational Institutes of Health
  8. 001: NINDS Exploratory Clinical Trials for Small Business (R44)

    Release Date: 06-15-2015Open Date: 08-05-2015 Due Dates: Multiple Close Date: 04-05-2018

    Purpose The NINDS is committed to advancing treatments for people burdened by the neurological disorders that fall under the NINDS mission. Traditionally, large pharmaceutical and biotechnology companies, as well as venture capital firms, have provided the resources needed to conduct the clinical studies required to fully develop and commercialize biomedical products and technologies. More recentl ...

    SBIR Department of Health and Human Services
  9. 001: NINDS Exploratory Clinical Trials for Small Business (R42)

    Release Date: 06-15-2015Open Date: 08-05-2015 Due Dates: Multiple Close Date: 04-05-2018

    Purpose The NINDS is committed to advancing treatments for people burdened by the neurological disorders that fall under the NINDS mission.  Traditionally, large pharmaceutical and biotechnology companies, as well as venture capital firms, have provided the resources needed to conduct the clinical studies required to fully develop and commercialize biomedical products and technologies. More r ...

    STTR Department of Health and Human Services
  10. Small Market Awards: SBIR Phase IIB Competing Renewals for Heart, Lung, Blood, and Sleep Technologies with Small Commercial Markets (R44)

    Release Date: 04-18-2016Open Date: 05-20-2016 Due Dates: Multiple Close Date: 06-20-2018

    Purpose The Small Business Innovation Research (SBIR) Program is an important National Institutes of Health (NIH) funding mechanism used to develop innovative solutions that address public health challenges. A major objective of the SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of biomedical technology products ...

    SBIR Department of Health and Human Services

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