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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.


If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).

  1. RFA-MD-21-006: Innovations for Healthy Living- Improving Minority Health and Eliminating Health Disparities (R43/R44- Clinical Trial Optional)

    Release Date: 03-11-2021Open Date: 04-05-2021Due Date: 05-03-2021Close Date: 05-04-2021

    Background Over the years, there has been continued improvement of health for Americans with the introduction of medical and scientific advances. Despite notable health improvements for the population as a whole through technological advancement, there continues to be an alarming disproportionate burden of illness among persons from racial and ethnic minority and other population groups who exper ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  2. PA-18-928 : Innovative Technologies for HIV Behavioral and Social Science Research (R43/R44 Clinical Trial Optional)

    Release Date: 09-19-2018Open Date: 12-05-2018 Due Dates: Multiple Close Date: 09-05-2021

    Background Technology-enabled HIV research has emerged in the past decade as a dynamic field that offers potential to bring HIV prevention and treatment efforts to scale. Technological innovations can help to reach vulnerable and at-risk populations such as minorities, adolescents, older adults, and individuals from rural settings who have challenges accessing conventional prevention and treatmen ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  3. SP4: In-space Manufacturing Technologies

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    SP4 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  4. IH: Instrumentation and Hardware Systems (IH)

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    The Instrumentation and Hardware Systems topic addresses the research and development of new and improved instrumentation and related systems for a wide variety of commercial and industrial applications. Proposals in this topic may deal with new instruments for use in scientific, industrial, engineering, or manufacturing environments, among others. Types of instruments that will be considered incl ...

    SBIRPhase INational Science Foundation
  5. IH1: Instrumentation or Hardware Systems for Actuation, Control, and Manipulation

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    IH1 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  6. IH2: Instrumentation or Hardware Systems for Detection and Characterization

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    IH2 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  7. IH3: Instrumentation or Hardware Systems for Imaging

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    IH3 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  8. S3: Integrated Circuit Design

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    S3 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
  9. PAR-20-244 : Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (SBIR) (R43/R44 Clinical Trial Not Allowed)

    Release Date: 06-25-2020Open Date: 08-04-2020 Due Dates: Multiple Close Date: 09-03-2022

    The educational objective of this FOA is to provide opportunities for eligible SBCs to submit NIH SBIR grant applications to develop IDM STEM products that address student career choice and health and medicine topics for: (1) pre-kindergarten to grade 12 (P-12) students and teachers or (2) informal science education (ISE) audiences. The second educational objective is to inform the American public ...

    SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health
  10. CH7: Interconnects

    Release Date: 02-12-2021Open Date: 02-12-2021 Due Dates: Multiple Close Date: 12-02-2021

    CH7 NSF SBIR Phase I (2021) National Science Foundation ...

    SBIRPhase INational Science Foundation
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